Sodium valproate (SV), an antiepileptic drug has several mechanism of action. It inhibits voltage sensitive Na+ channels and reduces intracellular Na accumulation. These actions are similar to that of both phenytoin and carbamazepine. We have investigated the direct cardiac action of SV and its effects on ouabain-induced arrhythmia in isolated guinea-pig atria. The guinea-pig atrium was dissect...

conclusions the authors emphasize on the rarity of this pathology among children, its clinical polymorphism, the necessity of a rapid diagnosis, and an appropriate treatment to avoid complications and recurrence of the tumor. introduction right atrial myxoma is a rare disease among children and its clinical presentation is not specific. case presentation we reported a four-year-old girl with ex...

OBJECTIVE Surgical repair of mitral insufficiency is most commonly performed through a left atriotomy via the inter-atrial groove or trans-atrial (septal) approach. While the dome of the left atrium approach has been described for mitral replacement concerns have been raised about its adequacy for complex repairs. We report our experience with mitral valve repair carried out through the dome of...

sodium valproate (sv), an antiepileptic drug has several mechanism of action. it inhibits voltage sensitive na+ channels and reduces intracellular na accumulation. these actions are similar to that of both phenytoin and carbamazepine. we have investigated the direct cardiac action of sv and its effects on ouabain-induced arrhythmia in isolated guinea-pig atria. the guinea-pig atrium was dissect...

Acute right ventricular failure is a life-threatening condition that can occur as result of sudden increase in total pulmonary vascular resistance, particular, embolism. Most patients with thromboembolism are treated thrombolytic therapy, but some cases open thrombextraction preferred. Removal blood clots from the bed and cardiopulmonary bypass lead to spasm artery elevation which, turn, increa...

Introduction. The existence of human cardiac stem cells (hCSC) and their regenerative capacity are not fully defined. The aim of this study was to identify and analyse the distribution of hCSCs by flow cytometry (FCM). Methods. Tissue samples from the left ventricle (LV) and the appendages of the right atrium (RA) and left atrium (LA) were taken during cardiac surgery. Mononuclear cells (MNCs) ...