The clinical significance of isolated anti-HBc is still a challenge. To elucidate the real importance of this finding in our blood donors, an investigation algorithm was tested. One hundred and twelve isolated anti-HBc seropositive blood donors underwent clinical evaluation and retesting of HBV markers. Those who presented repeatedly reactive isolated anti-HBc, received a single dose of hepatit...

Diosgenin is a steroidal saponin isolated from dioscorea opposita, which has been proven to have anti-cancer, anti-inflammatory, anti-thrombotic and immune system modulating effects in large number of pharmacological tests. also one the important raw materials for synthesis drugs, structural modification diosgenin obtain derivatives can not only improve solubility dissolution, but enhance their...

results at high concentrations (40 and 100 μm), apoptosis was demonstrated and it was clearly more prominent in hepatocytes exposed to celecoxib loaded liposomes. conclusions our results showed that celecoxib loaded liposomes robustly induced apoptosis, an action that can potentially make it more relevant than the usual form for chemopreventive strategies and also may raise concerns about its t...

We revisit the propagation of classical scalar fields in a spacetime which is asymptotically anti-de Sitter. The lack global hyperbolicity underlying background gives rise to an ambiguity dynamical evolution solutions wave equation, requiring prescription extra boundary conditions at conformal infinity be fixed. show that only tha are compatible with hypothesis system isolated, as defined by (i...