Rhesus (Rh) isoimmunization presenting as severe neonatal hemolytic disease is rare in RhD negative primigravidas of Chinese ethnicity. We report the case of a 32-year-old pregnant Taiwanese woman, RhD negative, who gave birth vaginally to two RhD-positive full-term fetuses 6 years apart. Antenatal follow-up was uneventful and there was no obvious fetal-maternal hemorrhage except at the perform...

1 Nicolaides KH, Soothill PW, Clewell WH, Rodeck CH, Mibashan R, Campbell S. Fetal haemoglogin measurement in the assessment of red cell isoimmunisation. Lancet 1988;i: 1073-5. 2 Rodeck CH, Nicolaides KH, Warsof SL, Fysh WJ, Gamsu HR, Kemp JR. The management of severe rhesus isoimmunisation by fetoscopic intravascular transfusions. Amj Obstet Gynecol 1984;150:769-74. 3 Nicolaides KH, Soothill P...

1. The specific radioactivity of [14C]cholesterol in plasma and in serial biopsies of muscle and skin was measured in Rhesus monkeys for 156 days after a single intravenous injection of [14C]cholesterol. 2. Analysis of the specific radioactitivy-time curves in terms of a two-compartment system indicated that all the cholesterol of muscle is exchangeable with the plasma cholesterol and that loca...

D'Souza SW. Neurodevelopmental outcome after birth asphyxia. In: Chiswick ML, ed. Recent advances in perinatal miedicine. Edinburgh: Churchill Livingstone, 1983:137-52. Rodeck CH, Holman CA, Karnicki J, et al. Direct intravascular fetal blood transfusion by fetoscopy in severe rhesus isoimmunisations. Lancet 1981 i:625-7. Liley AW. Liquor amnii analysis in the management of the pregnancy compli...

OBJECTIVE To measure atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) in control fetuses and fetuses with Rhesus isoimmunisation before and after intravascular transfusion. The current study was designed to investigate the response of ANP and BNP to cardiac short-term and long-term volume load in the human fetus. METHODS Fetal blood samples were collected from 18 human fet...

It is known that the pathological course of pregnancy associated with a disturbance in interdependent “mother-fetus” complex and leads to specific clinical consequences at molecular-cellular, tissue, organ, organismal population levels organization. In case violation placentation (placental barrier), state immune conflict occurs, characterized by an antigen-antibody reaction, carried out throug...

OBJECTIVE To develop national guidelines on the use of fetal Doppler in obstetrics. OPTIONS Whether umbilical cord artery, umbilical cord venous, ductus venosus, and middle cerebral artery Doppler are useful in assessing fetal health. OUTCOME Prediction of adverse perinatal outcome or prediction of fetal anemia. EVIDENCE MEDLINE search and review of bibliographies in identified articles. ...

T HE DEMONSTRATION OF A TRANSIENT MARROW GRAFT in a leukemic patient in 1956,’ and the treatment of victims of an irradiation accident in 1958,2 initiated a number of attempts to utilize allogeneic marrow grafts in patients with marrow failure or with leukemia. Recent reviews3’4 of those attempts show a notable lack of success with death due to failure of engraftment or to graft-vs-host disease...

OBJECTIVE While routine administration of rhesus (Rh) immunoglobulin has significantly reduced the incidence of Rh alloimmunization, maternal alloimmunization to other red cell antigens remains a contributor to perinatal morbidity and mortality. Although the Kell antigen is seen on the red cells of only 9% of the general population, attention to Kell antibodies continues to increase. CASE REP...