نتایج جستجو برای: ischemic tolerance

تعداد نتایج: 211039  

Journal: :Journal of Ocular Pharmacology and Therapeutics 2008

Journal: :Proceedings for Annual Meeting of The Japanese Pharmacological Society 2019

Journal: :Journal of Experimental Stroke & Translational Medicine 2009

Journal: :iranian journal of pharmacology and therapeutics 0
h. mirkhani p. fadakar

organic nitrates are commonly used in angina pectoris and ischemic cardiomyopathy. in order to optimize their effectiveness and patient convenience, several aspects must be observed. adequate doses, suitable dosage forms and asymmetric pattern of usage to prevent the nitrate tolerance are some factors that a physician must be familiar with. the objective of the present study was to define the p...

Journal: :The Journal of clinical investigation 1994
D L Osborne T Y Aw G Cepinskas P R Kvietys

In stable organ systems, such as the heart and kidneys, an oxidant stress induces an increase in endogenous antioxidant systems resulting in an increased resistance of the tissue to a subsequent oxidant challenge. The development of this oxidant tolerance requires 1.5-6 d. The aim of the present study was to determine whether oxidant tolerance can be induced in the small intestinal mucosa, a la...

Journal: :American journal of physiology. Heart and circulatory physiology 1999
Frank Grund Hilchen T Sommerschild Torstein Lyberg Knut A Kirkebøen Arnfinn Ilebekk

Coronary microembolization has been reported to increase coronary blood flow (CBF) through adenosine release. Because adenosine may increase ischemic tolerance against infarction, we tested the hypothesis that myocardial microembolization, a common finding in patients with ischemic heart disease, induces cardioprotection. Additionally, because the use of microspheres is a common tool to measure...

Journal: :Trials 2015
Elizabeth Osei Susanne Fonville Adrienne A M Zandbergen Paul J A M Brouwers Laus J M M Mulder Hester F Lingsma Diederik W J Dippel Peter J Koudstaal Heleen M den Hertog

BACKGROUND Impaired glucose tolerance is present in one third of patients with a TIA or ischemic stroke and is associated with a two-fold risk of recurrent stroke. Metformin improves glucose tolerance, but often leads to side effects. The aim of this study is to explore the feasibility, safety, and effects on glucose metabolism of metformin and sitagliptin in patients with TIA or minor ischemic...

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