In this work, Isatis tinctoria hairy root cultures (ITHRCs) were established as an alternative source for flavonoids (FL) production. I. tinctoria hairy root line V was found to be the most efficient line and was further confirmed by the PCR amplification of rolB, rolC and aux1 genes. Culture parameters of ITHRCs were optimized by Box-Behnken design (BBD), and eight bioactive FL constituents (r...

The methods of extraction, separation and analysis of alkaloids and indole glucosinolates (GLs) ofIsatis tinctoria were reviewed. Different analytical approaches such as High-pressure Liquid Chromatography (HPLC), Liquid Chromatography with Electrospray Ionization Mass Spectrometry (LC/ESI/MS), Electrospray Ionization Time-Of-Flight Mass Spectrometry (ESI-TOF-MS), and Nuclear Magnetic Resonance...

Woad (Isatis tinctoria), a long-known dye plant, is a noticeable source of indolic compounds, bioactive molecules exploitable as fine chemicals. Among these, glucobrassicin and its derivatives seem to play an antitumoral role, especially against mammary cancer. Since different Brassicaceae, such as broccoli and cauliflower, which are present in the human diet, contain glucobrassicin, it would b...

This paper discusses the design and implementation of a customizable distributed object-based runtime system. Our main goal in the system's design was to provide a distributed object-based system supporting execution of various (concurrent) object-oriented languages, and that can be easily enriched with mechanisms for object management so as to t the applications' needs. Enrichment of the runti...

kurdistan province in the western iran possesses varied climatic and geographical conditions that led to rich biodiversity. an investigation on the status of lizards in this province was carried out from june 2010 to september 2011. a total of 73 specimens were collected and identified. the collected specimens represented four families, 10 genera, and 14 species and subspecies, including agamid...