نتایج جستجو برای: isaba1

تعداد نتایج: 110  

Journal: :The Korean journal of laboratory medicine 2010
Sun Hoe Koo Kye Chul Kwon Hye Hyun Cho Ji Youn Sung

BACKGROUND The emergence of multidrug-resistant (MDR) Acinetobacter baumannii as an important opportunistic pathogen has given rise to significant therapeutic challenges in the treatment of nosocomial infections. In the present study, we assess the antibiotic resistance mechanisms of MDR A. baumannii strains by estimating the prevalence of antibiotic resistance determinants, including integrons...

Journal: :Indian Journal of Pharmaceutical Sciences 2022

The main objective is to study the genotypic and characterization of plasmid deoxyribonucleic acid content resistant isolates in Erbil city. A total 39 Acinetobacter baumannii were isolated from 102 diabetic foot ulcer patients, whose ages ranged 37 88 y, attending various medical wards hospitals city, Iraq, between May 2020 March 2021. Isolates tested for presence extended-spectrum beta-lactam...

Journal: :Antimicrobial agents and chemotherapy 2012
Shiro Endo Mina Sasano Hisakazu Yano Kazuaki Arai Tetsuji Aoyagi Masumitsu Hatta Yoshiaki Gu Mitsuhiro Yamada Koichi Tokuda Miho Ogawa Masahiro Shimojima Miho Kitagawa Hiroyuki Kunishima Yoichi Hirakata Mitsuo Kaku

Acinetobacter sp. has emerged as a major hospital pathogen (8). The greatest concern has been the emergence of carbapenem resistance in Acinetobacter baumannii by the acquisition of OXA-type carbapenemase or metallo-lactamases, since few effective antimicrobial agents exist. Several mechanisms can underlie carbapenem resistance in A. baumannii (1), but less is known about carbapenem resistance ...

Journal: :Antimicrobial agents and chemotherapy 2017
Agnese Lupo Pierre Châtre Cécile Ponsin Estelle Saras Henri-Jean Boulouis Nicolas Keck Marisa Haenni Jean-Yves Madec

Acinetobacter baumannii causes life-threatening infections in critically ill patients, with subsequent treatments mostly based on carbapenems. Unfortunately, oxacillinases (OXAs) that hydrolyze carbapenems, especially OXA-23, have dramatically spread in humans and even started to be reported in animals (1–4). As OXA-producing isolates are still rare in nonhuman sources, a comprehensive picture ...

2015
Steven J. Nigro Kathryn E. Holt Derek Pickard Ruth M. Hall

Sir, Worldwide, most multiply antibiotic-resistant (MAR), and particularly carbapenem-resistant, Acinetobacter baumannii causing infections belong to global clone 1 (GC1) or global clone 2 (GC2). Though there have been incidences where a different clonal group was predominantly responsible for an epidemic outbreak, MAR isolates that are not members of these clones have been observed to cause in...

Journal: :International Journal of Antimicrobial Agents 2021

Tigecycline is regarded as a last-resort treatment for multidrug-resistant Acinetobacter baumannii. However, tigecycline resistance in A. baumannii has increased worldwide. In this study, we investigated heteroresistance isolates from South Korea. Antibiotic susceptibility testing was performed on 323 nonduplicated isolates. Among 260 and 37 tigecycline-susceptible -intermediate-resistant isola...

Journal: :Journal of infection in developing countries 2013
Bruno Silvester Lopes Lucia Gallego Sebastian Giles Becket Amyes

INTRODUCTION Acinetobacter baumannii is opportunistic in debilitated hospitalised patients. Because information from some South American countries was previously lacking, this study examined the emergence of multi-resistant A. baumannii in three hospitals in Cochabamba, Bolivia, from 2008 to 2009. METHODOLOGY Multiplex PCR was used to identify the main resistance genes in 15 multi-resistant A...

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