DEAR EDITOR Blister beetle dermatitis is an irritant contact dermatitis, caused when beetles of the genus Paederus are crushed on the skin, releasing the vesicant pederin. It is also known as Dermatitis Linearis or Paedrous Dermatitis. It is characterized by the presence of erythematous and edematous lesions, pain and burning sensation, blisters, pustules and kissing lesions. Though blister bee...

Skin-infiltrating T-cells play a predominant role in allergic and inflammatory skin diseases such as atopic dermatitis, psoriasis and allergic contact dermatitis. These T-cells are attracted by several chemotactic factors including the chemokine CCL5/RANTES, a CC chemokine inducing both the migration and activation of specific leukocyte subsets. CCL5 has been found to be associated with various...

The effect of a protective cream was tested in a new tandem repeated irritation test with tandem application of 0.5% sodium lauryl sulphate (SLS) and undiluted toluene. The irritants were applied twice daily for 30 min to the ventral forearms of 20 volunteers. Irritant cutaneous reactions were quantified by a visual score, transepidermal water loss, chromametry and skin capacitance. Concurrent ...

INTRODUCTION Black-spot poison ivy is an uncommon clinical manifestation of contact with Toxicodendron plants. Unlike allergic contact dermatitis, which typically manifests in sensitized individuals within 2448 hours, the black lacquer that results from oxidation of the oleoresin after contact with the plant develops within hours of exposure and precedes allergic contact dermatitis, in some cas...

abstractpaederus dermatitis is an irritant contact dermatitis due to accidental contact by a beetle belonging to the genus paederus. in this study, clinical efficacies of s. ebulus fruit extract solution in patients affected by paederus dermatitis were evaluated. a randomized double-blind, prospective, placebo-controlled clinical trial was performed in 62 patients with clinical symptoms and sin...

PURPOSE To provide information from a literature review about the prevention, recognition, and treatment for contact dermatitis. TARGET AUDIENCE This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES After participating in this educational activity, the participant should be better able to:1. Identify signs and symptoms o...

A contact or exogenous dermatitis is one in which an external irritant is the m?st important cause; but a constitutional factor undoubtedly also plays a part, and accounts for the fact that only a certain proportion of a community, in contact with the same irritant, develops dermatitis. Most cases of contact dermatitis clear up quickly when the irritant is removed, but in some the rash persists...

PURPOSE OF REVIEW To describe recent developments in therapies which target the molecular mechanisms in atopic dermatitis. RECENT FINDINGS Current advances in the understanding of the molecular basis of atopic dermatitis are leading to the stratification of different atopic dermatitis phenotypes. New therapies offer the option to target-specific molecules involved in the pathophysiology of at...