Objective: Iron deficiency anaemia is a common problem in obstetrics throughout the developing World, despite fact that this largely preventable & easily treatable. The aim of study was to compare efficacy intravenous iron sucrose versus oral treatment anemia during pregnancy.Methods: 100 pregnant women with gestational age between 26 34 weeks mild moderate (Hb 7-10 g/dl) were selected. target ...

Kligler and Triple Sugar Iron (TSI) media have been considered to be interchangeable for the purpose of detecting hydrogen sulfide production in the family Enterobacteriaceae. Contrary evidence is presented in this report. From various sources, 11 cultures were isolated which yielded a positive hydrogen sulfide reaction on Kligler medium and a negative reaction on TSI. Biochemically, these cult...

Anemia is a very common clinical problem in patients with chronic kidney disease (CKD) and is associated with increased morbidity and mortality in these patients. Erythropoietin is a hormone synthesized that is deficient in the majority of patients with advanced kidney disease, thereby predisposing these patients to anemia. The other cause of anemia is deficiency of iron. Iron deficiency anemia...

Parenteral iron therapy is occasionally necessary for patients intolerant or unresponsive to oral iron therapy, for receiving recombinant erythropoietin therapy, or for use in treating functional iron deficiency. There are now three parenteral iron products available: iron dextran, ferric gluconate, and iron sucrose. We summarize the advantages and disadvantages of each product, including risk ...

BACKGROUND Iron deficiency anaemia is common in patients with chronic kidney disease, and intravenous iron is the preferred treatment for those on haemodialysis. The aim of this trial was to compare the efficacy and safety of iron isomaltoside 1000 (Monofer®) with iron sucrose (Venofer®) in haemodialysis patients. METHODS This was an open-label, randomized, multicentre, non-inferiority trial ...

Obstetricians then embarked on a series of research studies to combat anaemia in pregnancy. During 1970s they showed that (i) daily oral iron folate therapy (60 mg of elemental iron and 500 μg of folic acid) prevented fall in haemoglobin (Hb) levels seen in pregnancy and resulted in some improvement in birth weight, and (ii) daily administration of two or maximum tolerated dose of oral iron fol...

BACK GROUND Overt and subtle iron overload cause diabetes by lowering insulin production and promoting insulin resistance. Via divalent metal transporters pancreatic beta cells take up non-transferrin-bound iron which by catalyzing Fenton reaction can cause oxidative stress. Due to their strict dependence on mitochondrial glucose metabolism and limited antioxidant capacity, beta cells are exqui...