BACKGROUND Bone disorders (including osteoporosis, loosening of a prosthesis, and bone infections) are of great concern to the medical community and are difficult to cure. Therapies are available to treat such diseases, but all have drawbacks and are not specifically targeted to the site of disease. Chitosan is widely used in the biomedical community, including for orthopedic applications. The ...

BACKGROUND AND METHODS Magnetic iron oxide nanoparticles were prepared using a sonochemical method under atmospheric conditions at a Fe²⁺ to Fe³⁺ molar ratio of 1:2. The iron oxide nanoparticles were subsequently coated with chitosan and gallic acid to produce a core-shell structure. RESULTS X-ray diffraction demonstrated that the magnetic nanoparticles were pure Fe₃O₄ with a cubic inverse sp...

Microbial biofilms on biomaterial implants or devices are hard to eliminate by antibiotics due to their protection by exopolymeric substances that embed the organisms in a matrix, impenetrable for most antibiotics and immune-cells. Application of metals in their nanoparticulated form is currently considered to resolve bacterial infections. Gold and iron-oxide nanoparticles are widely used in di...

In this paper, we demonstrate the tunable T1 and T2 contrast abilities of engineered iron oxide nanoparticles with high performance for liver contrast-enhanced magnetic resonance imaging (MRI) in mice. To enhance the diagnostic accuracy of MRI, large numbers of contrast agents with T1 or T2 contrast ability have been widely explored. The comprehensive investigation of high-performance MRI contr...

The bimetallic Fe-Ru oxide nanoparticles were synthesized in the liquid-phase plasma (LPP) method which employed iron chloride and ruthenium chloride as precursors. The active species (OH·, Hα, Hβ, and O(I)) and the iron and ruthenium ions were observed in the plasma field created by the LPP process. The spherical-shaped bimetallic Fe-Ru oxide nanoparticles were synthesized by the LPP reaction,...

in this study, we synthesized herceptin conjugated magnetic nanoparticles (hmns) as an alternative probe to discover the levels of her2 (human epidermal growth factor receptor-2) in the surface of cells. these nanoparticles can be used by magnetic resonance imaging (mri) (non-invasive methods) for screening the patients with her2 positive or negative tumors. dextran coated iron oxide nanopartic...

results the maximum si was obtained at the highest applied flip angle (45°). the linear relationship between si and nanoparticle concentration was seen up to 112.21 and 98.83 μmol fe/l for the short (10°) and the long (45°) flip angles, respectively (r2 = 0.95). these values were reduced up to 48.54 and 42.73 μmol fe/l for these flip angles with r2 of 0.99. conclusions the maximum si will be in...

background: increased impervious surfaces in urban areas not only increase runoff volume and peak flow, but also worsen urban storm water pollution. the polluted runoff has many adverse impacts on human life and environment. the purpose of this study was to investigate and compare the efficiency of sand columns coated with nanoparticles of iron oxide in the presence and absence of a magnetic fi...

PURPOSE To evaluate spin-lock MR for detecting superparamagnetic iron oxides and compare the detection sensitivity of quantitative T1ρ with T2 imaging. METHODS In vitro experiments were performed to investigate the influence of iron oxide particle size and composition on T1ρ . These comprise T1ρ and T2 measurements (B0 = 1.41T) of agar (2%) with concentration ranges of three different iron ox...

in recent years, the scientists have focused on nanotecnology and its applications as the most important fields of research and development. the use of nanoparticles offers many advantages, due to their unique size and physical properties. magnetic iron oxide nanoparticles have been used in many fields, because of their unique properties such as large specific surface area and convenient separa...