AIMS To examine the evidence for excluding chronic hepatitis C (CHC) patients with substance abuse from treatment with interferon (IFN) and ribavirin. METHODS We reviewed clinical trials focussing on the treatment of chronic hepatitis C of patients with substance abuse between 2001 and 2004. Ten clinical trials concerning antiviral treatment in substance abusers were described of which six we...

abstract comorbidity of mental disorders and substance abuse has significant effect in treatment of persons with substance dependency. this research is aimed to determine the frequency of mental disorders in substance abusers. in cross-sectional descriptive design, 643 people were selected using convenience random sampling among patients with substance dependency that were undergoing treatment ...

OBJECTIVE To review the short-term and long-term outcomes of using heart donors with a history of substance abuse. METHODS Retrospective chart review was performed of heart recipients over an 8-year span. Charts provided demographics, mechanisms of donor death, and history of substance abuse. Additionally, charts were quarried for post-operative echocardiography and coronary angiogram results...

objectives to examine the military service predictors resulting in worsening drug abuse status. patients and methods a cross-sectional study with 3140 young soldiers was conducted in summer and autumn of 2010 and; the participants completed three questionnaires, namely the texas christian university drug screen (tcuds) ii, the addiction severity index and a questionnaire designed by the researc...

background: alcohol dependence (ad) is a major reason for morbidity and visits to emergency medical settings. however, the detection of ad is often difficult or overlooked. this study aimed to develop a brief screening questionnaire in hindi language for detection of ad in an emergency medical setting. methods:  the authors in consultation devised a set of questions related to ad in the hindi l...

conclusions present study demonstrated that the frequency of tobacco and substance abuse is considerable among iranian university students who thought to be more knowledgeable and concerned about their health. thus, efficient educational programs are needed to reduce the high-risk behaviors before students enter to university. background risky behaviors such as tobacco and substance abuse, whic...

aim and background: personality traits are among the factors affecting the tendency to substance abuse. personality evaluations have shown sensation seeking to be a particularly strong predictor of initial substance abuse across a variety of drug use categories. the aim of this study was to determine levels of sensation seeking in addicted and normal subjects while considering gender. methods a...