It is well recognized that intrauterine growth restriction leads to the development of insulin resistance and type 2 diabetes mellitus in adulthood. To investigate the mechanisms behind this "metabolic imprinting" phenomenon, we examined the impact of maternal undernutrition on insulin signaling pathway and the ATP sensitive potassium channel expression in the hypothalamus of intrauterine growt...

This study aims to investigate the short-term efficacy and safety of Transcervical Resection of Adhesions (TCRA). The data of 68 patients with Intrauterine Adhesion (IUA) treated by TCRA from October 2011 to September 2013 in our hospital were analysed. The intrauterine contraceptive ring was placed after resection, and oestrogen replacement therapy was performed after surgery. After three-mont...

OBJECTIVE To evaluate the efficacy and safety of two low-dose levonorgestrel intrauterine contraceptive systems. METHODS Nulliparous and parous women aged 18-35 years with regular menstrual cycles (21-35 days) requesting contraception were randomized to 3 years of treatment with one of two levonorgestrel intrauterine contraceptive systems: 13.5 mg total content or 19.5 mg total content. The p...

ectopic pregnancy (ep) is a potentially life-threatening condition in which the embryo implants outside the uterine endometrial cavity. abdominal pregnancy is an atypical site wherein the product of conception lies totally outside the reproductive tract. primary abdominal pregnancy is a very rare condition with a high mortality rate. diagnosis is often late or misdiagnosed. the aim of introduci...

background: implantation is considered as the rate-limiting step in success of assisted reproduction techniques, and intrauterine insemination cycles. it might be affected by ovarian superovulation and endometrial local scratching. objective: this study aims to investigate the effect of local endometrial injury on the outcome of iui cycles. materials and methods: in this randomized clinical tri...

The cause of infertility is unexplained in about 22-28% of all infertile couples. The prognosis for spontaneous pregnancy in such couples is better than in those with diagnosed causes of infertility. Traditional treatment options in this group have included expectant management, clomifene citrate, intrauterine insemination with (super ovulation plus intrauterine insemination) or without (intrau...

BACKGROUND Intrauterine device (IUD) migration and colon perforation is a rare but serious complication occurring sometimes years after insertion. Laparoscopic removal of a colon-perforating device is a seldom-used approach. CASE A 35-year-old presented with right upper quadrant (RUQ) abdominal pain one year following intrauterine device (IUD) insertion. Upon vaginal examination, no IUD strin...