BACKGROUND Intraoperative radiotherapy (IORT) constitutes a paradigm shift from the conventional 3-5 weeks of whole-breast external beam radiotherapy (EBRT). IORT enables delivery of radiation at the time of excision of the breast tumour, targeting the area at highest risk of recurrence, while minimizing excessive radiation exposure to healthy breast tissue. The rationale for IORT is based on t...

OBJECTIVE To present our experience since November 2013, and case selection criteria for intraoperative boost radiotherapy (IObRT) that significantly reduces the local recurrence rate after breast conserving surgery in patients with breast cancer. MATERIAL AND METHODS Patients who were suitable for IObRT were identified within the group of patients who were selected for breast conserving surg...

A new approach to intraoperative radiotherapy makes use of a mobile electron linear accelerator delivering therapeutic radiation doses in an operating room suite. This unconventional technology has raised questions concerning protection for personnel and the necessity of shielding the adjoining areas. In this study, the leakage and scatter radiation from the mobile electron accelerator is measu...

Intraoperative radiotherapy (IORT) for breast cancer has challenged the standard external beam radiotherapy (EBRT) and has been shown to be non-inferior for treating early breast cancer in the past decade. Several technologies have been tested for IORT and various randomised controlled trials are still ongoing. Different methods of application of IORT have also been evaluated, from early breast...

Surgery is the standard of care for patients with renal-cell carcinoma (RCC). Radiotherapy (RT) can decrease the risk of local recurrence after surgery and can lead to excellent outcomes in patients unfit for surgery. We reviewed clinical experience with various forms of RT, including conventional fractionated RT and intraoperative radiotherapy (IORT) as adjunct to surgery, hypofractionated hig...

a bstract   background: there are a few studies about commissioning mothers’ understanding from the surrogacy during 9 months of waiting for delivery in iran and other countries. this study was conducted with an aim to explore and explain the nature of concerns (experiences) of commissioning mothers. materials and methods:  a qualitative design with a conventional content analysis approach was ...