OBJECTIVES To determine whether the bovine eye develops elevation of intraocular pressure (IOP) in response to topical corticosteroid use and to develop a reliable model of steroid-induced elevation of IOP in an animal. METHODS Intraocular pressure was monitored by Perkins applanation tonometry in a group of 12 cows receiving topically administered prednisolone acetate in 1 eye 3 times a day ...

PURPOSE To investigate diurnal intraocular pressure (IOP) fluctuation in eyes with angle-closure. MATERIALS AND METHODS Seventy-seven eyes of 77 newly diagnosed patients with angle closure [33 subjects with primary angle-closure suspects (PACS), 23 subjects with primary angle-closure (PAC), and 21 subjects with primary angle-closure glau-coma (PACG)] were enrolled after laser peripheral irido...

A total of 104 eyes undergoing intraocular surgery were studied to investigate the effect on intraocular pressure (IOP) of peribulbar and retrobulbar anaesthesia in eyes with and without glaucoma. Forty eyes had glaucoma. Intraocular pressure was measured before, immediately after, and 5 minutes after injection of local anaesthetic. Mean IOP rose by 5.8 mm Hg at 1 minute (p < 0.01) and 0.7 mm H...

PURPOSE The aim of this study was to develop a system for the continuous recording of the intraocular pressure (IOP) in rabbits maintained in their normal environment. A telemetric system originally designed for the measurement of cardiovascular parameters in unrestrained, conscious laboratory animals was adapted for this purpose. METHODS Experiments were performed in adult albino female rabb...

AIMS To investigate the feasibility and to compare three devices measuring intraocular pressure (IOP) in mucopolysaccharidosis patients (MPS): iCare rebound tonometer (RT), Perkins applanation tonometer (PAT) and ocular response analyzer (ORA). METHODS MPS patients who underwent at least two examinations out of: RT, PAT and ORA at the same visit were identified and retrospectively analyzed in...

BACKGROUND Phacoemulsification and intraocular lens (IOL) implantation has resulted in early visual rehabilitation, increased wound stability and improved refractive results. Viscoelastic substances (VES) are important adjuncts in this type of surgery. Use of VES in phacoemulsification can be associated with adverse effects, the most common and potentially dangerous of which is the transient ri...

Eyes with normal-pressure glaucoma and those with high-pressure glaucoma can show a similar optic nerve head appearance, while eyes with vascular optic neuropathies show a markedly different optic disc appearance. Factors in addition to intraocular pressure (IOP) may thus play a role in the pathogenesis of glaucomatous optic neuropathy. Clinical and experimental studies showed that (1) physiolo...

PURPOSE To develop a protocol to measure the intraocular pressure (IOP) of living mice and to determine the IOP of genetically different mouse strains. METHODS Eyes of anesthetized animals were cannulated with a very fine fluid-filled glass microneedle. The microneedle was connected to a pressure transducer, and the pressure signal was analyzed with a computer system. Intraocular pressures of...

Glaucoma is defined as the increase in the intraocular pressure (IOP) causing visual loss due to the circulation deficits of the aqueous humor. The IOP measurement can be obtained without any problem in calm animals. However, some animals do not allow IOP measurement without sedation or anesthesia. The purpose of this study is to determine the effect of xylazine HCl (as a sedative) and ketamine...

purpose: to compare the tono-pen and schiotz tonometers in measurement of intraocular pressure (iop) in patients with primary congenital glaucoma. methods: this study was conducted on 38 eyes of 20 patients with primary congenital glaucoma. all measurements were performed under general anesthesia. one minute after receiving halothane 3% iop was determined by tono-pen and then by schiotz tonomet...