نتایج جستجو برای: intramolecular mechanics
تعداد نتایج: 154261 فیلتر نتایج به سال:
The p53 inhibitor MDMX is controlled by multiple stress signaling pathways. Using a proteolytic fragment release (PFR) assay, we detected an intramolecular interaction in MDMX that mechanistically mimics the interaction with p53, resulting in autoinhibition of MDMX. This mimicry is mediated by a hydrophobic peptide located in a long disordered central segment of MDMX that has sequence similarit...
We calculated intramolecular interaction energies of DNA by threading DNA sequences around crystal structures of nucleosomes. The strength of the intramolecular energy oscillations at frequency approximately 10 bps for dinucleotides was in agreement with previous nucleosome models. The intramolecular energy calculated along yeast genome positively correlated with nucleosome positioning experime...
This paper presents an original interactive analysis method consisting of mathematical calculation based on theoretical mechanics and mechanics of materials, and dynamics simulation for quantifying outrigger reaction forces of a kind of hydraulic mobile crane, aiming to avoid the eventualities during normal operation as far as possible, for example, tipping-over. First, a three dimensional dyna...
In this paper by analyzing the penetration mechanics of the segmented rods into semi-infinite ceramic targets, a mathematical model is provided to predict segmented rod projectiles penetration into semi-infinite ceramic targets. In analysis three factors of segments length, segments distance and number of segments are considered. Results suggest that the most important factor in penetration dep...
An efficient and environmentally friendly procedure for one-pot synthesis of 13-acetyl-9-methyl-11-ox-8-oxa-10,12-diazatricyclo [7.3.1. ] trideca-2,4,6-triene from salicylaldehyde, acetylaceton and urea via Biginelli condensation and intramolecular Michael-addition by using magnesium bromide as an expensive and easily available catalyst under solvent-free condition is desired. The structural el...
The phase space which is related to the motion of massive particle on 1+3- De sitter space is a 3-dimensional complex sphere. Our main aim in this study is discribing this movement in the frame quantum mechanics. Transfering from classical mechanic to quantum mechanics is possible by means of coherent states. Thus, after determination of this state, we quantize some of the classical observables.
Key words neutral homoaromatics - intramolecular Buchner reaction dearomatization photoswitch
Background: The emerging world of work requires the acquisition of a set of non-technical competencies with technical competencies in a career for sustainable employment. This paper aims at designing and validating a model for integrating the ethical components with technical competencies in curriculum based on competency in industrial mechanics’ branch. Method: The research approach is based ...
Social bonds are necessary for many mammals to survive and reproduce successfully. These bonds (i.e. pair-bonds, friendships, filial bonds) are characterized by different periods of development, longevity and strength. Socially monogamous species display certain behaviors not seen in many other mammals, such as adult pair-bonding and male parenting. In our studies of prairie voles (Microtus och...
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