PURPOSE Currently, no studies exist, which attest the suitability of the ovine intervertebral disc as a biomechanical in vivo model for preclinical tests of new therapeutic strategies of the human disc. By measuring the intradiscal pressure in vivo, the current study attempts to characterize an essential biomechanical parameter to provide a more comprehensive physiological understanding of the ...

OBJECTIVES To assess the reliability of intradiscal pressure measurement during in vitro biomechanical testing. In particular, the variability of measurements will be assessed for repeated measures by considering the effect of specimens and of freezing/thawing cycles. METHODS Thirty-six functional units from 8 porcine spines (S1: T7-T8, S2: T9-T10, S3: T12-T11, S4: T14-T13, S5: L1-L2 and S6: ...

conclusions altogether, ozone had significant positive effects on patients with disk herniation unresponsive to other conservative and minimally invasive treatments. background disk herniation (dh) is one of the most common disk lesions, inducing low back pain (lbp). various therapeutic options have been proposed for treatment of disk herniation (dh). intradiscal injection of ozone has been sug...

Study Design Systematic review. Objectives Degenerative disc disease and spondylosis resulting in radiculopathy and retrodiscal myelopathy are among the most frequently encountered cervical spinal disorders. Traditionally, anterior cervical discectomy and fusion (ACDF) has successfully achieved neural decompression and restored intradiscal height in these conditions. Unfortunately, nonunion a...

Practical PAIN MANAGEMENT, January/February 2007 ©2007 PPM Communications, Inc. Reprinted with permission. Diagnostic Provocation Discographic Injections Lumbar provocation discography remains a controversial diagnostic technique; and even more so with cervical/ thoracic discography. To appreciate the historical controversy surrounding discography is to understand that its inception was a tenuo...