Fifteen nuclear magnetic resonance (NMR) studies of 14 patients with herniated lumbar intervertebral disks were performed on the UCSF NMR imager. Computed tomographic (CT) scans done on a GE CT/T 8800 or comparable scanner were available at the time of NMR scan interpretation. Of the 16 posterior disk ruptures seen at CT, 12 were recognized on NMR. Diminished nucleus pulposus signal intensity w...

In the original description of herniated intervertebral disk by Mixter and Barr [1), the term used was rupture of the inter-vertebral disk. However, with the passage of time, this term, although used frequently by surgeons, has become meaningless. A rupture of the disk is a common finding at autopsy when the disks are examined, but ruptures are not necessarily associated with herniation of the ...

During the past 7 years we have had the opportunity of studying 27 cases of a condition characterized by multiple calcification of hyaline and fibrous cartilage both of the joints and of the intervertebral disks.* We present in this paper a detailed nosographical analysis of this clinical entity which we have named articular chondrocalcinosis (AC). Up to 1955, when we saw our first cases, we fo...

Spine-related pain and disability are some of the greatest preoccupations of clinicians and patients. Beyond`normal' aging of the elements of the spine, absolute degeneration of these spinal substructures eventually occurs. This at some point entails a superoinferior narrowing and eventual collapse of the intervertebral disk. Preceding or accompanying these diskal alterations, significant degen...

Introduction In veterinary medicine, intervertebral disk surgery is limited to the herniated intervertebral disk which may be situated at any level of the vertebral column, with surgical treatment differing according to the level. At the cervical level of the vertebral column, a ventral corpectomy is the technique of choice as the hernia is most often ventral. When the hernia is lateralized, a ...

The authors gratefully acknowledge the financial support provided by a Rutgers University Research Council grant and a generous grant from the FINRA (formerly NASD) Investor Education Foundation (#2005-08).

The Trps1 gene codes for an atypical member of the GATA type family of transcription factors. Mutations in human TRPS1 lead to the tricho-rhino-phalangeal syndrome types I and III, which are characterized by craniofacial and skeletal abnormalities and disturbed hair development. Correspondingly, during mouse embryonic development strong Trps1 expression is found in the cartilage condensations, ...

A successful model to study both herniated intervertebral disks and spinal operations such as laminectomy has not been described. Two procedures were developed in nonhuman primates: One produces an elevated nerve root simulating a herniated disk; the second is a laminectomy that simulates the operation in humans. Twenty-five surgical procedures were performed with no complications. A myelograph...