background: hairdressers are occupationally exposed to a number of agents in their workplace that result in respiratory symptoms and changes in pulmonary function. objective: to evaluate associations between occupational exposure and respiratory function and reported symptoms in a group of hairdressers compared to a control group. methods: a questionnaire on respiratory symptoms and workplace c...

OBJECTIVES This study aimed to develop a physiologically based pharmacokinetic model for chlorobenzene and to investigate the effect of variation in exposure to chlorobenzene on the chlorobenzene concentration in blood and the urinary concentration of 4-chlorocatechol. METHODS A physiologically based pharmacokinetic model was developed and the simulated results of urinary 4-chlorocatechol con...

A study of occupational exposure to paraquat was performed among 11 knapsack spray operators at banana plantations in Costa Rica. External and internal exposures were quantified and determinants of exposure identified by measurements, observations, and interviews. Dermal exposure was measured with skin pads, respiratory exposure by personal air sampling, and internal exposure by urine sampling....

The identification of occupational carcinogens in the workplace is a major concern of epidemiologists. A novel case-control approach has been developed which includes as a key component the assessment of a subject's occupational exposure history by a two stage process. Firstly, the subject is interviewed to obtain a detailed lifetime job history. Then a team of chemists and hygienists, hired an...

After the Chernobyl Nuclear Power Plant accident, the residents living around the Chernobyl were revealed to have been internally exposed to 137Cs through the intake of contaminated local foods. To evaluate the current situation of internal 137Cs exposure and the relationship between the 137Cs soil contamination and internal exposure in residents, we investigated the 137Cs body burden in reside...

AIMS To determine sperm nuclear DNA integrity and to investigate the relation between fenvalerate (FE) exposure and spermatozoa DNA damage. METHODS Sperm DNA fragmentation was detected by a modified alkaline single cell gel electrophoresis (Comet) assay and a terminal deoxynucleotidyl transferase mediated dUTP nick end labelling (TUNEL) assay. The olive tail moment (OTM) and percentage tail D...