A cross sectional study was carried out at various hospitals of Faisalabad city. The aim of current study was to investigate the prevalence of β-thalassemia disease in hospital population related to age, consanguinity and anti-HCV antibody positivity. For this purpose, 300 patients were interviewed for the different parameters including specific type of β-thalassemia disease, their family histo...

problem owing to the wide prevalence of the disease in these regions.[1] β thalassemia is inherited as an autosomal recessive disorder, which results in reduction or absence in β globin chain.[2] Point mutation in the β-globin gene is the cause of β thalassemia inheritance in majority of cases, while short deletion in the same gene may occasionally be the cause. More than 200 mutations that res...

Five strains of Prevotella intermedia were examined for their ability to coaggregate with various gram-positive and gram-negative species of oral bacteria. Two of the P. intermedia strains coaggregated with selected Actinomyces species, P. intermedia 27 with Actinomyces viscosus T14V and Actinomyces naeslundii ATCC 12104, PK606, PK984, and PK947, and P. intermedia 113 with Actinomyces odontolyt...

introduction: thalassemia is common in iran. appropriate therapy for this disease includes a regular blood transfusion and chelation therapy. however, patients will inevitably confront with side effects, particularly iron overloads in critical organ including heart, ductless glands and liver. this study tries to determine the prevalence of diabetes mellitus in transfusion dependent β thalassemi...

During a blood meal, Lutzomyia intermedia sand flies transmit Leishmania braziliensis, a parasite causing tegumentary leishmaniasis. In experimental leishmaniasis, pre-exposure to saliva of most blood-feeding sand flies results in parasite establishment in absence of any skin damages in mice challenged with dermotropic Leishmania species together with saliva. In contrast, pre-immunization with ...

OBJECTIVE The diverse clinical phenotype of hemoglobin E (HbE)/β-thalassemia has not only confounded clinicians in matters of patient management but has also led scientists to investigate the complex mechanisms involved in maintaining the delicate red cell environment where, even with apparent similarities of α- and β-globin genotypes, the phenotype tells a different story. The BTB and CNC homo...

Inspite of the recent progress in the endocrinology of the anterior pituitary, a specific part of the adenohypophysis which is in a close contact with the neurohypophysis, i.e., the pars intermedia, has been left in a state of incomplete understanding both in morphology and physiology. For example, early reports by ITANO (1936) and BAILLIF (1938) dealing with the rat pars intermedia, indicated ...