نتایج جستجو برای: interleukin 1β
تعداد نتایج: 105629 فیلتر نتایج به سال:
Chronic tophaceous gout is the end stage of gout. We employed a blockade of interleukin-6 signaling therapy by tocilizumab instead of anakinra, an interleukin-1 receptor antagonist, for a 61-year-old Japanese woman diagnosed with tophaceous gout. Laboratory data showed that serum interleukin-6 concentration was elevated. Serum interleukin-1β concentration was under the detectable level, althoug...
BACKGROUND Systemic inflammation has been linked to a failure to normalize CD4(+) T-cell numbers in treated human immunodeficiency virus (HIV) infection. Although inflammatory cytokines such as interleukin 6 (IL-6) are predictors of disease progression in treated HIV infection, it is not clear how or whether inflammatory mediators contribute to immune restoration failure. METHODS We examined ...
ABSTRACT Chronic kidney disease (CKD) represents an independent risk factor for cardiovascular diseases (CVD). Accordingly, CKD patients show a substantial increased of mortality. Inflammation important link between and CVD. The interaction endothelial cells effector the innate immune system plays central role in development progression inflammation. Vascular injury causes dysfunction, leading ...

 Purpose: To determine the effect of ursolic acid (UA) on diabetes-induced cognitive defect, as well its mechanism action in streptozotocin (STZ)-induced diabetic rats.
 Methods: A rat model diabetes was established by administration STZ. The rats received UA via gastric perfusion for 56 successive days. Learning and memory functions were assessed using Morris water maze. Superoxide ...
Aim. To study the relationship of coronary microvascular dysfunction (CMD) with levels pro- and anti-inflammatory biomarkers in patients preserved ejection fraction (LVEF) non-obstructive artery disease (CAD). Material methods . The included 118 (70 men, mean age, 62,0 [58,0; 69,0] years) LVEF (62 [59; 64] %) CAD. Serum N-terminal pro-brain natriuretic peptide (NT-proBNP), high-sensitivity C-re...
PURPOSE To examine the expression of pro-interleukin-1β (pro-IL-1β) and interleukin-1β (IL-1β) in the vitreous body of patients with neovascular age-related macular degeneration(nAMD), polypoidal choroidal vasculopathy (PCV), proliferative diabetic retinopathy (PDR), retinal vein occlusion (RVO) or Eales' disease to further elucidate the role of IL-1β and inflammation in the pathogenesis of neo...
Postoperative cognitive decline is a clinical syndrome. Volatile anesthetics are commonly used during surgery. It is conceivable that volatile anesthetics may contribute to postoperative cognitive decline. Isoflurane can impair cognitive functions of animals under certain conditions. However, the mechanisms for this impairment are not clear. Here, male 18-month old Fisher 344 rats or 10-week ol...
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