background: delayed graft function is a main complication after deceased donor kidney transplantation that adversely affects graft outcome. difficulties in prediction and early detection of delayed graft function have hindered the ability to perform proper therapeutic interventions. we investigated whether measuring urinary interleukin 18 and neutrophil gelatinase-associated lipocalin as marker...

Background: The protective effect of the chloroform extract of Cyperus rotundus (CHCR) is attributed to its anti-inflammatory and antioxidant activities. Cytokines, important regulators of inflammation and repair, play a key role in the pathogenesis of inflammatory bowel disease (IBD). Targeting these cytokines can effectively ameliorate the symptoms of IBD. The aim of the present study was to ...

Background Generalized convulsive epilepsy (GCE), an important subtype of epilepsy, is a syndrome neuronal dysfunction characterized by diffuse abnormal discharge neurons within the brain. Compounding evidence suggests correlation between and inflammatory factors, for instance, cyclooxygenase-2, interleukin-1β, interleukin-6. Elevated levels factors have been observed in patients with several a...

ABSTRACTAim: To evaluate the effect of intra-canal cryotherapy on interleukin-1βand interleukin-10 expression in teeth with symptomatic apical periodontitis.Methodology: Forty-eight single rooted patients periodontitiswere randomly divided into 4 groups according to irrigation protocol.Group I (control); 5% sodium hypochlorite at room temperature. Group II; coldsodium (2-5°C). III; final rinse ...

Background: Increased levels of interleukin-8 (IL-8) and interleukin-6 (IL-6) in acute human brucellosis have been reported. Previous studies have shown that the production and level of IL-6 and IL-8 cytokines are associated with the polymorphism of the encoding genes. Objective: To investigate the probable association between IL-6 (-174 C/G) and IL-8 (-251 A/T) gene polymorphisms and susceptib...

This study aimed to investigate the efficacy and the underlining mechanism of aspirindesensitization among patients with Aspirin Exacerbated Respiratory Disease (AERD). Thirtyeightpatients, who had undergone an aspirin challenge test and were diagnosed as havingAERD, were engaged in a double-blind randomized clinical trial. They were divided into twogroups—an active group of patients who went t...

Background As COVID-19 immunomodulation has been a part of interest for studies, it found that severe coronavirus disease 2019 (COVID-19) is associated with hyper-inflammatory response and increased levels interleukin-6 (IL-6) interleukin-10 (IL-10). This can progress to cytokine storm syndrome eventually development acute respiratory distress (ARDS). Interleukin-1 receptor antagonist (IL-1RA) ...

The current study examined the relationship between renal cell carcinoma-related risk and gene polymorphisms in interleukin-10, vitamin D receptor cytochrome P450 1A1 genes. Using preferred reporting items for systematic reviews meta-analyses criteria, link carcinoma was studied by utilizing Web of Science, Embase, PubMed Wanfang databases. CC TT genotypes along with interleukin-10-819C/T C-all...