نتایج جستجو برای: interferon β

تعداد نتایج: 243008  

Journal: :Journal of the American Society of Nephrology 2007

Journal: :CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2000
P W O'Connor

Technology: Cytokineand antigen-based immunosuppressive therapies for multiple sclerosis. Use: In the last decade partially effective disease-modifying drugs for multiple sclerosis (MS) have finally emerged. All require self-injection and include interferon-β (Betaseron, Avonex and Rebif) and glatiramer acetate (Copaxone). In general, these agents reduce the frequency of MS relapses by onethird...

Journal: :iranian journal of immunology 0
saeid abediankenari department of microbiology and immunology, faculty of medicine, mazandaran university of medical sciences, sari, iran davoud shaker department of microbiology and immunology, faculty of medicine, mazandaran university of medical sciences, sari, iran farshideh abedian department of microbiology and immunology, faculty of medicine, mazandaran university of medical sciences, sari, iran arazmohammad mirabi department of microbiology and immunology, faculty of medicine, mazandaran university of medical sciences, sari, iran

background: dendritic cells (dc) are a key regulator of the immune response, and interferon- beta (ifn-β) is considered an immunomodulatory molecule for dc. objective: the purpose of this study was to evaluate the ability of ifn-β treated dc to induce cytokine secretion by cd4+ t cells. methods: dendritic cells were generated from blood monocytes with granulocyte-monocyte colony-stimulating fac...

2017
Anita K. Bakrania Bhavesh C. Variya Snehal S. Patel

As a novel target for breast cancer, interferon inducers have found its role as anti-angiogenic agents with diethylaminoethyl dextran (DEAE-Dextran) being a molecule used for centuries as a transfection agent. Our results herein offer an explanation for the emergence of DEAE-Dextran as an anti-tumor agent for TNBC with in-depth mechanistic approach as an anti-angiogenic molecule. DEAE-Dextran h...

Journal: :Folia neuropathologica 2011
Grażyna Michałowska-Wender Justyna Biernacka-Łukanty Zofia Lasik Lukasz Jernas Mieczysław Wender

Interleukin 17 (IL-17) and its receptor IL-17R1 produced by T-helper cells named Th17 are involved in the pathology of autoimmune diseases. In contrast to the at least partially explained role of IL-17 in pathology of multiple sclerosis, the significance of IL-17R in MS is unclear. Therefore we have studied the expression of IL-17R in the stable phase of multiple sclerosis treated by interferon...

Journal: :Antimicrobial Agents and Chemotherapy 2021

Davoudi-Monfared et al. (1) report in this journal the results from a clinical trial on coronavirus disease 2019 (COVID-19) patients showing that subcutaneous administration of interferon beta (IFN-β) was associated with more rapid recovery severe acute respiratory syndrome 2 (SARS-CoV-2) infection and decreased mortality. These findings have been corroborated by two recent phase trials during ...

Journal: :Emerging Infectious Diseases 2004

2014
Chae-Hwa Yoo Ji-Hyun Yeom Jin-Ju Heo Eun-Kyung Song Sang-Il Lee Myung-Kwan Han

Lipopolysaccharide (LPS), an endotoxin derived from gram-negative bacteria, promotes the secretion of proinflammatory cytokines and mediates endotoxemia through activation of mitogen activated protein kinases, NF-κB, and interferon regulatory factor-3. Silent information regulator transcript-1 (SIRT1), an NAD-dependent deacetylase, mediates NF-κB deacetylation, and inhibits its function. SIRT1 ...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید