The observed physiological dynamics of an infant receiving intensive care are affected by many possible factors, including interventions to the baby, the operation of the monitoring equipment and the state of health. The Factorial Switching Kalman Filter can be used to infer the presence of such factors from a sequence of observations, and to estimate the true values where these observations ha...

To cite: Sharma D, Pandita A, Murki S, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2014-206577 DESCRIPTION Cases A term male baby with an Apgar score of 8/8/9 was admitted to our hospital at 24 h of life with abnormal body movements. The infant had multifocal myoclonic seizures that started in the lower limbs with secondary generalisation to the whole ...

OBJECTIVE To determine the effect of early enteral feeding on the outcome of critically ill medical patients whose hemodynamic condition is unstable. METHODS Prospectively collected data in a multi-institutional medical intensive care unit database were analyzed retrospectively. A total of 1174 patients were identified who required mechanical ventilation for more than 2 days and were treated ...

Disorders of the urea cycle are secondary to a defect in the system that converts ammonia into urea, resulting in accumulation of ammonia and other products. This results in encephalopathy, coma, and death if not recognized and treated rapidly. Late-onset urea cycle disorders may be precipitated by acute disease and can be difficult to recognize because patients are already ill. Diagnosis of ur...

Takotsubo cardiomyopathy is increasingly being diagnosed as a cause of acute coronary syndrome in postmenopausal women. It may also present as reversible acute left heart failure with an excellent prognosis for recovery. Although rare, it may be an underdiagnosed condition in the medical intensive care units among patients admitted with non-cardiac acute conditions. Therefore, intensivists must...

Central Pontine Myelinosis (CPM) and Extra Pontine Myelinosis (EPM) are debilitating conditions, resulting from the rapid correction of hyponatremia. The outcome and prognosis of this medical condition are variable; mainly involving functional decline from neuro-musculoskeletal upset. An intensive, multidisciplinary rehabilitation has played an essential role in facilitating and hasten recovery...

Cerebral Arterial Gas Embolism (CAGE) is a serious condition, which tends to occur as an iatrogenic complication of numerous invasive medical and surgical procedures performed in esthesia intensive care