JCB • VOLUME 208 • NUMBER 6 • 2015 652 Johanna Ivaska will tell you that she never planned to continue studying integrins, the sticky transmembrane receptors that grab onto a cell’s extracellular environment, after her PhD. But somehow the integrins seemed to be stuck on her. As a PhD student at the University of Turku in Finland, Ivaska chose a laboratory investigating collagen-binding integri...

objective: considering the importance of integrin molecules in the implantation and lack of sufficient information in the expression pattern of these molecules in various phases of estrous cycle. it seemed to be necessary to investigate these molecules in mouse endometrial during the various phases of oestrous cycle. materials and methods: female nmri mice (n=15) aged 6-8 weeks were studied. v...

Introduction: In order to study the alterations of beta 1 and 2 integrins mRNA level in rat lumbar spinal cord following the induction of chronic pain and its effect on the development of tolerance to morphine analgesia, we examined the level of expression of these genes in the presence of chronic pain, which is an inhibitor of morphine tolerance. We used induction of chronic pain alone and in ...