Nucleosome traversal by RNA polymerase II (pol II) and recovery of chromatin structure after transcription are essential for proper gene expression. In this paper we show that nucleosomes assembled with Sin mutant histones present a much weaker barrier to traversal by pol II and are less likely to survive transcription. Increases in traversal from incorporation of Sin mutant histones and histon...

This paper proposes a new method for Network Address Translator (NAT) Traversal in UDP. Several techniques have been proposed for traversing NAT or firewall boxes in UDP. These techniques can establish UDP communication between hosts behind NATs. However, existing NAT traversal methods, including Universal Plug and Play (UPnP), Simple traversal of UDP over NATs (STUN) and Teredo, cannot travers...

Background: The fatal effect of ionizing radiation on cells depends on Linear Energy Transfer (LET) level. The distribution of ionizing radiation is sparse and homogeneous for low LET radiations such as X or γ, but it is dense and concentrated for high LET radiation such as heavy-ions radiation. Material and Methods: Chinese hamster ovary cells (CHO-K1) were exposed to 4 Gy Fe-ion 2000 keV/...

Emulation of one architecture on another is useful when the architecture is under design, when software must be ported to a new platform or is being developed for systems which are still under development, or for embedded systems that have insufficient resources to support the software development process. Emulation using an interpreter is typically slower than normal execution by up to 3 order...

In this paper we review the traversal algorithms for kd-trees for ray tracing. Ordinary traversal algorithms such as sequential, recursive, and those with neighbor-links have different limitations, which led to several new developments within the last decade. We describe algorithms exploiting ray coherence and algorithms designed with specific hardware architecture limitations such as memory la...

We present an orthogonal topological framework which is able to provide incidence traversal operations for all topological elements. The run-time performance of this topological traversal operations can be optimized at a highly expressive level, where the abstraction penalty imposed by this approach is negligible. For the topological storage we use vertex-cell as well as cell-vertex incidence i...