The two canine adenoviruses, infectious canine hepatitis (ICH) virus and infectious canine laryngotracheitis (ICL) virus (also designated as Toronto A26/61 virus), were studied with respect to their morphology and the biological properties of their soluble components. The two viruses were found to be composed of soluble components similar to, and carrying biological activities corresponding to,...

A 3698 bp region of the genome of infectious laryngotracheitis virus (ILTV) was sequenced and found to contain the entire glycoprotein gB gene and the C-terminal region of a gene homologous to the ICP 18.5 protein gene of herpes simplex virus type 1. The ILTV gB gene encoded a protein with an Mr of 100K possessing all the characteristics of a transmembrane glycoprotein. Alignment of the ILTV gB...

1. The characteristic lesions of infectious laryngotracheitis are ordinarily restricted to the respiratory tract and are most pronounced in the larynx and trachea. Sometimes the eyelids are affected. A certain percentage of the cases are associated with bronchitis and peribronchitis, pneumonic areas and hemorrhages in the lung, while the involvement of the nasal passages, communicating sinuses,...