Infection due to Plasmodium falciparum is a serious public health threat in sub-Saharan Africa. Malaria endemic foci are often times affected by other infectious agents which may contribute to the clinical episodes of the disease.1 Hepatitis B virus is one of such infectious agents that coexist with P. falciparum in most endemic areas. Although the accurate infection status due to hepatitis B v...

Recently the production of infectious hepatitis and homologous serum jaundtice in human volunteers afforded an unusual opportunity to study changes in hepatic function during this disease.3" This study permitted initial control measurements of liver function to be made before inoculation with icterogenic material. Changes in liver function occurring during the disease could also be followed unt...

Hepatitis B virus (HBV) presents a higher residual risk of transmission by transfusion than hepatitis C virus (HCV) or human immunodeficiency virus (HIV). While most infectious blood units are removed by screening for hepatitis B surface antigen (HBsAg), there is clear evidence that transmission by HBsAg-negative components occurs, in part, during the serologically negative window period, but m...

Burden of Viral Hepatitis on Human Health Compared to better-publicized infectious diseases such as HIV or malaria, viral hepatitis is often referred to as a silent killer. • Of the five hepatitis viruses (A-E), hepatitis B, C, and D viruses cause chronic liver disease leading to cirrhosis, liver failure and liver cancer. Hepatitis B, C and D viruses, transmitted through blood and body fluids, ...

By COMMANDER HAROLD A. LYONS (MC) USN, AND L’r. (JG) J. GRANT HARRISON (MC) USN T HE DEMONSTRATION in 1932. by Paul and Bunnell’ that the blood serum of patients with the sporadic form of infectious mononucleosis contained antibodies against sheep erthrocytes in concentrations far above a normal titer was an important advance in the study and diagnosis of this disease. It gave a good test for t...

Only three cases of infectious lymphocytosis have been described as such in the English literature. Elsewhere about 70 cases have been described, almost entirely in the American literature. As the disease may be more common in England than the recorded'cases would seem to indicate, it was thought worthwhile to report a case, review the literature and discuss the differential diagnosis with part...

The study of serum transaminases has recently entered clinical practice. In December, 1954, Wroblewsky and La Due demonstrated an increase of glutamic-oxalacetic (GOT) transaminase in the serum of patients suffering from various liver diseases and in carbon tetrachloride intoxication. In 1955, de Ritis, Coltorti and Giusti demonstrated an increase of both aspartic-ketoglutaric (GOT) and alanine...