OBJECTIVE To quantify the incidence of and risk factors for neonatal jaundice among infants referred for care from a rural, low-resource, population-based cohort in southern Nepal. METHODS Study participants were 18,985 newborn infants born in Sarlahi District in southern Nepal from May 2003 through January 2006 who participated in a cluster-randomised, placebo-controlled, community-based tri...

BACKGROUND Hyperbilirubinaemia is a major cause of neonatal morbidity. Early identification of those infants most at risk might allow the development of targeted primary preventative therapy and follow-up. The objective of this study was to assess whether arterial umbilical cord bilirubin (aUCB) level at delivery predicts the development of neonatal jaundice in term deliveries. METHODS Retros...

INTRODUCTION The aim of this study was to evaluate the frequency of urinary tract infection (UTI) in neonates with prolonged jaundice. MATERIALS AND METHODS Newborn infants with jaundice lasted more than 2 weeks were included in this study. Patients who had other signs or symptoms were excluded. Workup of prolonged hyperbilirubinemia was performed, including direct Coomb's test, blood group o...

Background: Infant mortality remains a major developmental challenge in many low-income countries. Epidemiological evidence suggests that infant acquisition of maternal microbiome is essential for programming immunity and metabolism. As such, irrational antibiotic use may affect health.
 Objectives: The aim the study was to determine effects prenatal on early postnatal life (90 days) commu...

BACKGROUND AND OBJECTIVES Breastfed newborns are more likely to develop prolonged hyperbilirubinemia than those fed formula, but the prevalence of prolonged hyperbilirubinemia in a largely white, North American breastfed population is unknown. In this population, we documented the natural history of jaundice and the prevalence of prolonged hyperbilirubinemia, and we evaluated the utility of ass...

Although in most cases of haemolytic disease of the newborn practically all the bilirubin in the serum is of the indirect reacting type, a quarter of a century ago Still (1927) and Hawksley and Lightwood (1934) described cases in which the serum direct reacting bilirubin was raised and signs of obstructive jaundice appeared. This condition came to be known as the 'inspissated bile syndrome' (Hs...

BACKGROUND Mothers are frequently the first to observe the onset of jaundice in their newborn infants before the decision to seek treatment. However, simple-to-use tools that could facilitate early detection of jaundice and assist mothers to seek professional care, especially after hospital discharge, are rare. This study therefore, set out to evaluate the performance of a -two-color icteromete...

A3,520-g boy was born at 38 weeks gestation to a 32-yearold G1P1 woman. The mother had a temperature of 101°F at the time of delivery. It was a normal pregnancy, labor, and delivery. The baby was treated with antibiotics because of the mother’s fever. Initial blood count revealed hemoglobin of 18.3 g/dL; white blood cell count of 21,500/mm3 with 43% neutrophils, 4% bands, 4% metamyelocytes, 5% ...