BACKGROUND Few studies have examined the validity of administering tuberculosis control measures based on tuberculin skin test (TST) erythema measurement. The present study aimed to clarify the relationship between the erythema and the induration seen following TST and to evaluate the validity of diagnosing tuberculosis infection based on the erythema following TST in school-aged contacts who h...

Objective: To determine the clinical and epidemiological profile of patients who are candidates for TNF-α inhibitor use and are classified as having latent tuberculosis (LTB), as well as to evaluate the outcomes of prophylactic treatment with isoniazid. Methods: A prospective descriptive analysis followed by an analytical, observational, cross-sectional study of the outcomes of prophylactic tre...

BACKGROUND Military personnel are at risk for acquiring Mycobacterium tuberculosis infection because of activities in close quarters and in regions with a high prevalence of tuberculosis (TB). Accurate tests are needed to avoid unnecessary treatment because of false-positive results and to avoid TB because of false-negative results and failure to diagnose and treat M. tuberculosis infection. We...

THE development of erythema is often a striking feature of the reaction to tuberculin. It occurs in the cutaneous test of Von Pirquet, and its development was the criterion of positivity in the conjunctival test of Wolff-Eisner and Calmette. It is usually well developed in the test which superseded both of these, the intracutaneous test of Mantoux. Over the years, however, particularly with the...

Histoplasmin skin tests and dilated funduscopic examination for presumed ocular histoplasmosis were carried out on 842 individuals, aged 13 years and older, from Walkersville, Md. Seventy percent of the male and 51% of the female population were sensitive to the histoplasmin skin test; among reactors, males had a mean diameter of induration of 11.6 mm, and females had a mean induration of 9.7 m...

A total of 101 preterm infants between 26 and 37 weeks' gestation who received BCG vaccination at birth were evaluated between two and four months after vaccination. Altogether 32% of these infants had no visible BCG scar. All infants were then tested with tuberculin purified protein derivative (PPD) but only 70 returned for the test to be read 48-72 hours later. The test was negative in 22 (31...

The aim of this study was to compare the efficacy of the tuberculin skin test (TST) and the quantiferon test (QFT) for detecting latent tuberculosis infection (LTBI) in health care workers (HCWs). Seventy-six participants who were working in Duzce University Hospital, where tuberculosis patients were being treated, were included in the study. TST was performed according to the Mantoux technique...