the effect of microbial load on the condition index of the edible oyster, saccostrea cucullata were analysed on monthly basis during 2010 and 2011 from the three different stations (namkhana, frasergaunge and sajnekhali) of indian sundarbans. the results showed significant variation with respect to microbial load between stations and seasons, which is reflected in the tissue of edible oyster. s...

Although the role of nucleus accumbens (NAcc) dopamine (DA) in reward learning has been extensively studied, few investigations have addressed its involvement in learning socially relevant information. Here, we have examined the involvement of NAcc DA in social attachment of the "monogamous" prairie vole (Microtus orchrogaster). We first demonstrated that DA is necessary for the formation of so...

Humans can program and control movements, including breathing-related movements. On the electroencephalogram (EEG), this preparation is accompanied by a low-amplitude negativity starting approximately 2.5 s before inspiration that is best known as a Bereitschaftspotential (BP). The presence of BPs has been described during the compensation of mechanical inspiratory loading, thus identifying a c...

Progressive collapse is defined as the spread of an initial failure from element to element, eventually resulting in the collapse of an entire structure or a disproportionately large part of it. The current progressive collapse analyses and design methods in guidelines and codes focus on the alternate load path method. This method is suitable especially in the case of blast-induced progressive ...

The regulatory pathways involved in the rapid response of the AP-1 transcription factor, c-fos, to mechanical load in human primary osteoblast-like (HOB) cells and the human MG-63 bone cell line were investigated using a four-point bending model. HOB and MG-63 cells showed upregulation of c-fos expression on fibronectin and collagen type I substrates; however, MG-63 cells did not respond on lam...

Peake, M. A., L. M. Cooling, J. L. Magnay, P. B. M. Thomas, and A. J. El Haj. Selected Contribution: Regulatory pathways involved in mechanical induction of c-fos gene expression in bone cells. J Appl Physiol 89: 2498–2507, 2000.—The regulatory pathways involved in the rapid response of the AP-1 transcription factor, c-fos, to mechanical load in human primary osteoblast-like (HOB) cells and the...

Previous studies have shown a preferential loss of grey matter in fronto-temporal regions in patients with multiple sclerosis. Studies of correlates of disease severity are more controversial, because some studies have suggested an association between sensorimotor cortex atrophy and Expanded Disability Status Scale score, while others did not find such a correlation. The objective of this study...

Although the perceptual load theory of attention has stimulated a great deal of research, evidence for the role of perceptual load in determining perception has typically relied on indirect measures that infer perception from distractor effects on reaction times or neural activity (see N. Lavie, 2005, for a review). Here we varied the level of perceptual load in a letter-search task and assesse...

Inhibiting complement anaphlytoxin C5a during sepsis may prevent sepsis mortality. Although human anti-C5 antibodies exist, their therapeutic use in microbial sepsis has been avoided because of the hypothesis that inhibiting C5b will prevent formation of the bactericidal membrane attack complex (MAC) and worsen clinical outcome. We wished to test the hypothesis that inhibition of C5 would impro...