نتایج جستجو برای: indolent

تعداد نتایج: 5476  

2012
Barbara Legius Kristel Van Landuyt Patrick Verschueren Rene Westhovens

A septic arthritis due to an indolent infection is a challenge for timely diagnosis. In recent years septic arthritides due to Staphylococcus Warneri are increasingly reported, mostly as a complication in patients with prosthetic devices. We report on a case of a 38 year old immunocompetent male with an indolent infection with this commensal of the skin after a stay at an intensive care unit an...

Journal: :Haematologica 2008
Caroline Bodet-Milin Françoise Kraeber-Bodéré Philippe Moreau Loïc Campion Benoît Dupas Steven Le Gouill

Positron emission tomography using 18F-fluorodeoxyglucose (FDG-PET) has been successfully evaluated in the management of non-Hodgkin's lymphoma (NHL).1-3 Histological transformation (HT) of indolent lymphoma is a dramatic event that occurs in 5-10% of the patients and carries a dismal prognosis.4,5 Previous studies prove that indolent lymphoma entities show a lower FDG uptake when compared with...

Journal: :Current hematologic malignancy reports 1998
Lubomir Sokol Thomas P Loughran

Clonal diseases of large granular lymphocytes (LGLs) represent a spectrum of clinically rare lymphoproliferative malignancies arising from either mature T-cell (CD3(+)) or natural killer (NK)-cell (CD3(-)) lineages. The clinical behavior of these disorders ranges from indolent to very aggressive. Patients with symptomatic indolent T-cell or NK-cell LGL leukemia are usually treated with immunosu...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2015
C Madsen M B Pedersen M Ø Vase K Bendix M B Møller P Johansen B A Jensen P Jensen L Munksgaard P D Brown E K Segel F A d'Amore

BACKGROUND Transformation of indolent lymphomas (IL) to an aggressive histology (TIL) often results in a rapid clinical course, treatment refractoriness and shortened survival. Although rituximab-containing regimens (R-chemo) have become standard of care in CD20-positive TIL, the role of autologous stem-cell transplantation (ASCT) is still debated. The purpose of this study was to determine whe...

2017
Jyothi S Prabhu Aruna Korlimarla C E Anupama Annie Alexander Rohini Raghavan Roma Kaul Krisha Desai Savitha Rajarajan Suraj Manjunath Marjorrie Correa R Raman Anjali Kalamdani MSN Prasad Shekar Patil K S Gopinath B S Srinath T.S. Sridhar

Hormone receptor positive (HR+) breast cancers are a heterogeneous class with differential prognosis. Although more than half of Indian women present with advanced disease, many such patients do well. We have attempted identification of biologically indolent tumors within HR+HER2- tumors based on gene expression using histological grade as a guide to tumor aggression. 144 HR+HER2- tumors were d...

Journal: :Clinical genitourinary cancer 2014
Francesca Giunchi Eugenio Brunocilla Marco Borghesi Simona Rizzi Martina Sofia Ricci Daniele Romagnoli Giuseppe Martorana Riccardo Schiavina Michelangelo Fiorentino

INTRODUCTION/BACKGROUND The increase of prostate cancer diagnosis after the introduction of prostate-specific antigen (PSA) screening resulted in overtreatment of patients with low risk tumors. The histological Gleason score (GS) revised in 2005 by the International Society of Urological Pathology (ISUP) is currently the most reliable tool to separate aggressive from indolent prostate cancer. ...

Journal: :International journal of clinical and experimental pathology 2014
Fang Yang Tengfei Liu Haiyan Zhao Zhiyan Hu Liwei Xiao Yanping Liu Xiaoyan Wang Zuguo Li

T-lymphoblastic lymphoma (T-LBP) is a high-grade malignant lymphoma, which possesses the characteristic of high metastasis and high mortality without treatment. We are presenting a special T-lymphoblastic proliferation involving in the oropharynx, nasopharynx, sinus and trachea in a patient with local involved about 15-years without systemic dissemination. The immunophenotype of this case was s...

2001
Elena Adinolfi Loredana Melchiorri Simonetta Falzoni Paola Chiozzi Anna Morelli Alessia Tieghi Antonio Cuneo Gianluigi Castoldi Francesco Di Virgilio Olavio R. Baricordi

Human leukocytes express a receptor for extracellular nucleotides, named P2X7R, that in lymphocytes can either mediate cell death or proliferation, depending on the level of activation. The authors have investigated P2X7R expression and function in 21 patients affected by B-cell chronic lymphocytic leukemia, 13 with an evolutive and 8 with an indolent variant of the disease. Resting cytoplasmic...

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