A simple and rapid stability indicating method based on capillary zone electrophoresis has been developed and validated for the analysis of buserelin (BUS). The best separations were achieved by using a bare fused silica capillary (75 m i.d.; 65.5 cm total, 57.0 cm effective length), phosphate buffer (pH = 3.00; 26.4 mM), at 35 °C. The sample was hydrodynamically injected at 50 mbar for 5 seco...

fluvoxamine maleate is a selective serotonin reuptake inhibitor, which is used for the treatment of different types of depressive disorders. in the present study, a stability indicating hplc method was developed and validated for the determination of fluvoxamine maleate. the chromatographic separation was carried out using a nova-pak cn column and a mixture of k2hpo4 50 mm (ph 7.0) and acetonit...

this paper describes two rapid, sensitive and specific methods for the determination of fulvestrant in pharmaceutical preparations by high performance liquid chromatography (hplc) and linear sweep voltammetry (lsv). hplc method was used to study the degradation behaviour. fulvestrant was subjected to degradation under the conditions of hydrolysis (acid and alkali), oxidation (30% h2o2). the lin...

a simple and rapid stability indicating method based on capillary zone electrophoresis has been developed and validated for the analysis of buserelin (bus). the best separations were achieved by using a bare fused silica capillary (75 m i.d.; 65.5 cm total, 57.0 cm effective length), phosphate buffer (ph = 3.00; 26.4 mm), at 35 °c. the sample was hydrodynamically injected at 50 mbar for 5 seco...