Ischemia-reperfusion injuries (IRI) occur in different clinical conditions such as stroke, trauma, organ transplantation, and so on. Ischemia damages mainly arise from oxygen depletion in tissues. The lack of oxygen as the last acceptor of electron in the respiratory chain causes a decrease in ATP production and eventually leads to disruption of membrane transport, acidosis, cellular edema and ...

BACKGROUND Inappropriate use of multiple medicines (inappropriate polypharmacy) is a major challenge in older people with consequences of increased prevalence and severity of adverse drug reactions and interactions, and reduced medicines adherence. The aim of this study was to determine the levels of consensus amongst key stakeholders in the European Union (EU) in relation to aspects of the man...

Red clover (Trifolium pratense L.) is used as a source for isoflavone (IF) dietary supplements. In this study, we focused on the red clover IF irilone (IRI), because of its reported comparatively high bioavailability. Because the conjugative metabolism plays a key role in the elimination of IF, we investigated the species-specific differences and glucuronidation kinetics of IRI using different ...

preparing long term reformatory plan for the health system, like other macro plans, requires guiding principles which is according to the values, and as a bridge, connect the ideals and values to the goals. this study was designed with the purpose of explaining the values and principles of health system, and as a pre-requisite to compilation of iran's health system reform plan at 2025.the docum...

The aim of the research is to analyze philosophy 2023 Education Vision Document Ministry National in line with opinions educators. was carried out on principals and teachers working different educational institutions (preschool, primary, secondary high school) a province Western Black Sea Region. It regarded include participants from various levels research. SMART Goals technique used form semi...

The purpose of this document is to re ect on novel and upcoming methods for computer vision that might have relevance for application in robot vision and video analytics. The document covers many di erent subelds of computer vision, most of which have been addressed by our research activity at the computer vision laboratory. The report has been written based on a request of, and supported by, FOI.

access to the right to the highest attainable level of health is a constitutional right that obliges governments and other players to take step to increase all individuals' chances of obtaining good health. at the least, health and education are two crucial requirements for this as well. iran's vision 2025 is going to lead the country to a developed state with the highest rank of economic, scie...

Objective(s): Hydrogen sulfide (H2S) attenuates ischemia-reperfusion injury (IRI) in different organs. However, its mechanism of action in renal IRI remains unclear. The present study investigated the hypothesis that H2S attenuates renal IRI via the induction of heat shock proteins (HSPs).Materials and Methods: Adult Wistar rats were subjected to unilateral renal ischemia for 45 min followed by...

Kidney ischemia and reperfusion injury (IRI) is associated with a high mortality rate, which is attributed to tubular oxidative and nitrative stresses; however, an effective approach to limit IRI remains elusive. Spermidine, a naturally occurring polyamine, protects yeast cells against aging through the inhibition of oxidative stress and necrosis. In the present study, spermidine supplementatio...