four known flavonoids: quercetin 3-o-β-d-rutinoside (q3rut), myricetin 3-o-β-d-galactopyranoside (m3gal), quercetin 3-o-β-d-galactopyranoside (q3gal) and quercetin 3-o-β-d-glucopyranoside (q3glc), for the first time were isolated from aerial parts of euphorbia microsciadia. the chemical structure of them was elucidated on the basis of 1 and 2 d-nmr spectra and different spectroscopic techniques...

objective: homalium letestui pellegr (flacourtiaceae) is used in traditional medicine in parts of nigeria for the treatment of malaria, ulcer, and inflammatory diseases and as an aphrodisiac. this investigation was aimed to evaluate the cytotoxic, immunomodulatory, and antileishmanial properties of stem extract and fractions of homalium letestui (h. letestui). materials and methods: cytotoxic a...

Department of Surgery, UMDNJ-New Jersey Medical School, Newark, NJ 07103, USA Department of Pharmacology, Institute of Experimental Medicine, Hungarian Academy of Sciences, PO Box 67, H-1450 Budapest, Hungary Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 10/11N311, 10 Center Drive, Bethesda, MD 20892-1892, USA Inotek Pharmaceutic...

introduction: multiple sclerosis (ms) has been recognized as a common neurodegenerative disease that occurs after an auto reactive t cells against myelin antigens.  demyelination and inflammation are the main features of this disease. the anti-inflammatory and neuroprotective roles of bone marrow-derived mesenchymal stem cells (bm-mscs) have been considered as a suitable treatment against autoi...