interleukin-1β (il-1β), the prototypical pro-inflammatory cytokine, is produced by macrophages following exposure to bacterial products. its role is to act upon several cell types at the site of infection to stimulate the production of pro-inflammatory molecules that will cause increase in vascular permeability. therefore, il-1β regulates the initiation and development of acute inflammation tha...

In this paper, we study the right regular representation RΓ of a finite group G on the vector space consisting of vector valued functions on Γ\G with a subgroup Γ of G and give a trace formula using the work of M.-F. Vignéras.

the pathogenesis of bipolar i disorder (bp-i) involves immune-mediated mechanisms, especially an imbalance in pro-inflammatory/anti-inflammatory cytokines in plasma or cerebrospinal fluid. interleukin-1 (il-1) gene cluster, coding some of these pro-inflammatory cytokines, might play a role in various neuropathologies related to neuron inflammation. the aim of the present study was to investigat...

objective(s):with regard to pharmacological effects of carvacrol on the respiratory system, its effect on cytokines genes expression in splenocytes of asthmatic mice was examined in this study. materials and methods:splenocytes were isolated from non-sensitized (control group), sensitized mice to ovalbumin (ova) (group s), and s animals treated with dexamethasone, and three concentrations of ca...

objective(s): interleukin-12 (il-12) as a cytokine has been proved to have a critical role in stimulating the immune system and has been used as immunotherapeutic agents in cancer gene therapy. chitosan as a polymer, with high ability of binding to nucleic acids is a good candidate for gene delivery since it is biodegradable, biocompatible and non-allergenic polysaccharide. the objective of the...

objective(s):il-12 as an anti-tumor cytokine and il-33 a novel identified cytokine with both pro- or anti-tumor activities, play important roles in response against tumor cells. our aim was to evaluate the il-12 and il-33 levels and single nucleotide polymorphisms (snp) in their genes in patients with breast cancer. materials and methods:blood samples were collected from 100 patients with breas...

Bachground: Endometriosis is a disease of female genital system, which is defined by the presence of ectopic endometrial tissue outside the uterine cavity. IL-8 is an autocrine growth factor in the endometrium that contributes to the pathogenesis of endometriosis. The aim of this study was to investigate the association between -251T/A polymorphism in the IL-8 gene and endometriosis risk in Ira...

IL-36Ra, a member of the IL-1 family, is an antagonist IL-36 receptor and inhibitory regulator cascade. Loss function mutations in IL36RN gene, which encodes have been demonstrated to enhance cascade subsequently activation MAPK NF-κB pathways, resulting neutrophil recruitment pustule formation skin by increased production chemokines such as IL-8 CXCL-1. Cutaneous inflammation caused dysregulat...