نتایج جستجو برای: igg response
تعداد نتایج: 1005651 فیلتر نتایج به سال:
These last months, dozens of SARS-CoV-2 serological tests have become available with varying performances. A major effort was completed to compare 17 in April 2020 Switzerland. In a preliminary phase, we compared IgG, IgM, IgA and pan Ig including ELISA, LFA, CLIA ECLIA on panel 182 sera, comprising 113 sera from hospitalized patients positive RT-PCR, 69 sampled before 1st November 2019, expect...
The kinetics of the generation of primed IgM and IgG antibody-forming cell precursors, and of helper T-cell populations, were analyzed in mice whose primary responses to high and low doses of SRBC were arrested at intervals by the immunosuppressive agents cyclophosphamide monohydrate and specific antibody. The extent to which immunological memory was established in these animals before blockade...
Background Immunosuppressive medication reduces the immunogenicity of coronavirus disease 2019 (COVID-19) vaccines in patients with rheumatic and musculoskeletal diseases (RMDs). However, underlying mechanism remains unclear. The primary aim our study was to dissect impact immunosuppressive on cellular humoral immune responses RMD receiving inactivated COVID-19 vaccine. Methods A total 28 five ...
Key Points • Peptide assemblies on MPLAcontaining liposomes induce IgG responses independent of T cells, CD40L, CD28, CD14, and MyD88. • Direct stimulation of B cells through TLR4 and TRIF is required for T cell–independent IgG responses. Immunoglobulin class switching from IgM to IgG in response to peptides is generally T cell–dependent and vaccination in T cell–deficient individuals is ineffi...
toxoplasma gondii is one of the most prevalent parasitic infections in world. rh, ned and me49 are of the most prevalent clonal types of the parasite isolated till now. differences in pathogenicity and virulence of different types have been investigated in different studies. no controlled study was performed to compare the ability of different types to initiate humoral immune response. we inves...
OBJECTIVE It has been suggested that autoantibodies in systemic sclerosis (SSc) may induce the differentiation of cultured fibroblasts into myofibroblasts through platelet-derived growth factor receptor (PDGFR) activation. The present study aims to characterize the effects of SSc IgG on vascular smooth muscle cells (VSMCs) and to determine if stimulatory autoantibodies directed to the PDGFR can...
BACKGROUND Ulcerative colitis (UC) is a chronic inflammatory bowel disease in which the colonic mucosa is infiltrated with plasma cells producing IgG autoantibodies. It is not known whether this represents a local mucosal response which has switched to IgG or a peripheral response which may have been initiated by peripheral antigen which homed to the colonic mucosa. The clonal distribution of I...
Background: Ulcerative colitis (UC) is a chronic inflammatory bowel disease in which the colonic mucosa is infiltrated with plasma cells producing IgG autoantibodies. It is not known whether this represents a local mucosal response which has switched to IgG or a peripheral response which may have been initiated by peripheral antigen which homed to the colonic mucosa. The clonal distribution of ...
The evaluation of human antibody response specific to arthropod saliva may be a useful marker of exposure to vector-borne disease. Such an immunologic tool, applied to the evaluation of the exposure to Glossina bites, could be integrated in the control of human African trypanosomiasis (HAT). The antibody (IgG) response specific to uninfected Glossina fuscipes fuscipes saliva was evaluated accor...
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