BACKGROUND Core myopathies are a clinically and genetically heterogeneous group of congenital myopathies with the common defined histopathological feature of focally reduced oxidative activity on muscle biopsy. It has a low incidence, however, recent articles show broad clinical spectrum, suggesting that the real incidence should be considerably larger than previously described. Due to the impo...

Background In 2004, the U.S. Preventive Services Task Force (USPSTF) recommended against the routine screening of asymptomatic adolescents for idiopathic scoliosis (IS). The stated rationale in the Summary of the Recommendation was “the USPSTF concluded that the harms of screening adolescents for idiopathic scoliosis exceed the potential benefits.” [1] Since that time, at least five states have...

STUDY DESIGN Systematic review. OBJECTIVE The aim of the study was to determine the predictive value of combined multimodality somatosensory evoked potential (SSEP) and transcranial motor evoked potential (TcMEP) monitoring in detecting impending neurological injury during surgery for idiopathic scoliosis. SUMMARY OF BACKGROUND DATA The diagnostic of motor evoked potential monitoring and SS...

In this paper, we take physical and health integration as the entry point. Firstly, based on transformation mechanism of adolescent idiopathic scoliosis construct a time delay differential model. Moreover, using theory characteristic equation discuss stability positive equilibrium under delays τ=0 τ≠0. Furthermore, through numerical simulation, it has been verified delay, τ, exceeds critical va...

Materials and methods Material consisted of 52 consecutive patients with idiopathic scoliosis that visited The Department of Pediatric Orthopaedics (out-patients and hospitalized) between February 1st and December 31st 2010. The mean age of the patients was 14 years (8,4 – 18,9). There were 48 girls and 4 boys. All the patients were examined by an orthopaedic surgeon (trunk rotation measured by...

AIMS This study is to determine if expression level of microRNA-143 (miR-143) and cyclooxygenase-2 (COX-2) are related to the occurrence and development of degenerative scoliosis. METHODS A total of 30 patients with degenerative scoliosis, 30 patients with adolescent idiopathic scoliosis were enrolled in this study. For control, 30 patients with spinal burst fractures were also enrolled in th...

Scoliosis, by its most basic definition, is a musculoskeletal deformity of the spine characterized by an observable lateral curvature [1]. The diagnosis known as Adolescent Idiopathic Scoliosis (AIS) was first defined by John James in 1954 as he attempted to divide childhood idiopathic scoliosis into three peak periods of incidence. Adolescent onset was described as the appearance of scoliosis ...

Of 42 patients with resolving infantile idiopathic scoliosis, 34 were followed up for more than 25 years. Twenty had been primarily treated in a plaster bed and 14 by physiotherapy. The mean angle of the curve at presentation was 17 degrees and at follow-up it was 5 degrees. No patient had significant progression of the scoliosis during the growth spurt. When adults few had back pain or an incr...