AIM To establish the frequency of Y chromosome microdeletions in an unselected group of infertile Croatian men. METHODS An unselected group of 105 patients (male partners of infertile couples), both with idiopathic and non-idiopathic infertility, consecutively referred to the outpatient infertility clinic, gynecology department, General Hospital Pula, Istria County, Croatia, was examined for ...

Infertility, considered as one of the main public health issues, affects about 10%-15% of the couples in reproductive age. Male factors are known to be responsible for 50% of all infertilities. It is well-established that the chromosomal abnormality is more prevalent in infertile men than in fertile men [1]. In developed countries, the incidence factor is considered to be less, when compared to...

infertility can be caused by an unexplained reduction in semen quality in males who present asnormal on physical examination and endocrine testing. there is some evidence that aberrantmetabolism of micronutrients such as choline may play a causative role in male factorinfertility. choline is a crucial factor in the regulation of sperm membrane structure andmotility, and this nutrient plays an i...

BACKGROUND Idiopathic infertility is a significant number of causes of male infertility. Empirical treatments are used for idiopathic male infertility, and antioxidant supplementation is a kind of management of oxidative stress related infertility. We investigated the antioxidant effects of the modified Ojayeonjonghwan (KH-204) in a rat model of cryptorchidism. METHOD Male rats were divided i...

AIM To study the incidence of single nucleotide polymorphisms in ubiquitin-specific protease 26 (USP26) gene and its involvement in idiopathic male infertility in China. METHODS Routine semen analysis was performed. Infertility factors such as immunological, infectious and biochemical disorders were examined to select patients with idiopathic infertility. DNA was isolated from peripheral bloo...

Background. Male infertility is one of the most serious medical and social problems. Idiopathic accounts for about 30 % cases infertile men. Rheumatoid arthritis associated with a decreased fertility potential. The aim present work was to determine lipid peroxidation level activity antioxidant enzymes such as glutathione peroxidase reductase in seminal plasma blood men idiopathic concomitant au...

The aim of this study was to evaluate the chromatin status in different groups of patients. Five groups of men were selected: pre-vasectomy; male factor infertility; varicocele; immunological male infertility; and idiopathic infertility. Chromatin status was evaluated using flow cytometry after staining the DNA with the fluorochrome propidium iodide. Differences were observed in the state of sp...

PURPOSE OF REVIEW The purpose of this review is to highlight the most important advances in the field of genetics of male infertility, with particular attention to primary articles dealing with the identification of new genetic and epigenetic markers that could be translated into clinical practice in the near future. RECENT FINDINGS Copy number variations (CNVs) of the Y chromosome (gr/gr) de...

Background Genetic factors are candidates for about 30% of male infertility with sperm production-related abnormalities. Y chromosome microdeletions are responsible for around 10% of male infertility. These microdeletions generally occur in azoospermia factor on the Yq. That is often associated with the quantitative reduction of sperm. Objective The aim of this cross-sectional study was to de...

Introduction and Aim: Idiopathic infertility accounts for at least 30% of all cases infertility, oxidative stress has been identified as a novel developing factor in idiopathic male infertility. Oxidative occurs when antioxidant defense mechanisms are outmatched by the creation reactive oxygen species (ROS). The purpose this research was to examine impact enzymatic antioxidants (catalase supero...