نتایج جستجو برای: ich
تعداد نتایج: 7722 فیلتر نتایج به سال:
The importance of alternative splicing in regulating apoptosis has been suggested by findings of functionally antagonistic proteins generated by alternative splicing of several genes involved in apoptosis. Among these, Ich-1 (also named as caspase-2) encodes a member of the caspase family of proteases. Two forms of Ich-1 are produced as a result of alternative splicing: Ich-1L, which causes apo...
Abstract Background: The role of serum lipid profile in development of intracerebral hemorrhage (ICH). The main purpose of current study was to compare the serum level of total cholesterol (TC), low-density cholesterol (LDL-CH), high-density cholesterol (HDL-CH) and triglysrides (TG) between patients with ICH and matched healthy subjects. Materials and methods: There were 116 patients with ICH ...
Intracerebral hemorrhage (ICH) is a common and often fatal subtype of stroke and produces severe neurological deficits in survivors. At present, there is lack of effective treatments that improve outcome in ICH. A neglected aspect of ICH research is the development of approaches that can be effectively used to improve recovery. Although previous studies have showed that thrombin induces blood-b...
Background: Stroke is a leading causes of death and disability globally and 10-15% of all strokes are caused by intracerebral hemorrhage (ICH). An increased knowledge of factors affecting prognosis after ICH is needed to guide the development of possible interventions to improve outcome. Aim: To investigate how clinical andimaging factors affect survival and functional outcome after ICH and how...
Timing for deep vein thrombosis chemoprophylaxis in traumatic brain injury: an evidence-based review
Multiple studies have addressed deep vein thrombosis chemoprophylaxis timing in traumatic brain injuries. However, a precise time for safe and effective chemoprophylaxis is uncertain according to experts. A comprehensive literature review on brain injuries was performed to delineate temporal proportions for 1) spontaneous intracranial hemorrhage (ICH) progression, 2) post-chemoprophylaxis ICH e...
BACKGROUND AND PURPOSE Intracerebral hemorrhage (ICH) has a 30-day mortality rate of 40% to 50% and lacks a proven treatment. We report a preplanned, midpoint analysis of the first population-based, case-control study that examines both genetic and environmental risk factors of ICH. METHODS We prospectively identified cases of hemorrhagic stroke at all 16 hospitals in the Greater Cincinnati/N...
BACKGROUND AND PURPOSE Our previous studies have demonstrated that oxidative DNA injury occurs in the brain after intracerebral hemorrhage (ICH). We therefore examined whether edaravone, a free-radical scavenger, could reduce ICH-induced brain injury. METHODS These experiments used pentobarbital-anesthetized, male Sprague-Dawley rats that received an infusion of either 100 microL autologous w...
Intracranial hemorrhage (ICH) is a rare but devastating complication of childhood immune thrombocytopenia purpura (ITP). A survey of ICH from 1987 to 2000 identified cases of ICH in childhood ITP in the United States. Forty patients with ICH and 80 matched ITP control subjects were accrued. The estimated incidence of ICH was 0.19% to 0.78%. Platelet counts were less than 20 x 10(9)/L in 90% and...
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