نتایج جستجو برای: i receptor

تعداد نتایج: 1572301  

Journal: :Endocrine Journal 2021

Testosterone deficiency is associated with poor prognosis among patients chronic heart failure (HF). Physiological testosterone improves the exercise capacity of HF. In this study, we evaluated whether treatment physiological contributes to anti-fibrogenesis by modifying calcium homeostasis in cardiac fibroblasts and studied underlying mechanisms. Nitric oxide (NO) analyses, (Ca2+) fluorescence...

Journal: :Journal of obstetrics, gynecology and cancer research 2022

Background & Objective: Breast cancer has a pivotal role in many deaths caused by malignancies. Epidermal growth factor receptor-2 (EGFR-2 or HER-2) and estrogen receptor (ER) have immense predictive values as prognostic factors. cancers that steroid receptors respond to hormone therapy show better prognosis than without receptors.Materials Methods: A retrospective cross-sectional study was per...

Journal: :Journal of Biological Chemistry 1983

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2013

Journal: :European Journal of Pharmacology 2021

The intracellular signaling pathway of growth hormone (GH)-stimulated DNA synthesis and proliferation was investigated in primary cultures adult rat hepatocytes. cell were detected hepatocyte parenchymal cells grown serum-free, defined medium containing GH (100 ng/ml). GH-stimulated almost completely blocked by TG101209 (10?6 M), a selective Janus kinase (JAK)2 inhibitor, U-73122 phospholipase ...

Journal: :مجله علوم اعصاب شفای خاتم 0
mohammad taghi farzad-fard neurology department, ghaem hospital, mashhad university of medical sciences, mashhad, iran

anti-n-methyl-d-aspartate receptor (anti-nmdar) encephalitis is is most common form ofimmune-mediated encephalitis with prominent neurologic and psychiatric features at disease onset. we describe a 16 years old patient who presented with fever and status epilepticus. his mri sequences was normal. anti-nmdar antibodies were detected in the csf.  mri, ct and other studies didn,t show any tumor.

Journal: :مجله علوم اعصاب شفای خاتم 0
shahin mohammad sadeghi sajad sahabnegah hadi kazemi zabihollah khaksar hadi aligholi mostafa modarres mousavi

dopamine (da) is one of the main catecholamines in the brain and is crucial for movement coordination, endocrine function, reward, mood, memory and emotions. the dopaminergic system is the primary therapeutic target in the treatment of parkinson’s disease (pd), drug addiction and schizophrenia. notwithstanding, dysfunction of central dopaminergic neurotransmission has also been associated to de...

Journal: :Zeitschrift fur Naturforschung. C, Journal of biosciences 1994
A P Mazurek G Karpińska

The determinants for recognition at H3 histamine receptors are considered. Findings based on quantum-chemical calculations suggest that H3 histamine receptor is less hydrophilic than the H2. The form most likely to be recognized by the H3 receptor is an intramolecularly hydrogen-bonded form of alpha-methylhistamine. Receptor environment and hydration effects of active form of histamine analogs ...

Journal: :IUPHAR/BPS guide to pharmacology CITE 2023

This receptor family comprises a group of receptors for the calcitonin/CGRP peptides. The calcitonin (CT), amylin (AMY), gene-related peptide (CGRP) and adrenomedullin (AM) (nomenclature as agreed by NC-IUPHAR Subcommittee on CGRP, AM, AMY, CT [131, 74, 71]) are generated genes CALCR (which codes receptor, CTR) CALCRL receptor-like CLR, previously known CRLR). Their function pharmacology altere...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید

function paginate(evt) { url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term pg=parseInt(evt.target.text) var data={ "year":filter_year, "term":term, "pgn":pg } filtered_res=post_and_fetch(data,url) window.scrollTo(0,0); } function update_search_meta(search_meta) { meta_place=document.getElementById("search_meta_data") term=search_meta.term active_pgn=search_meta.pgn num_res=search_meta.num_res num_pages=search_meta.num_pages year=search_meta.year meta_place.dataset.term=term meta_place.dataset.page=active_pgn meta_place.dataset.num_res=num_res meta_place.dataset.num_pages=num_pages meta_place.dataset.year=year document.getElementById("num_result_place").innerHTML=num_res if (year !== "unfilter"){ document.getElementById("year_filter_label").style="display:inline;" document.getElementById("year_filter_place").innerHTML=year }else { document.getElementById("year_filter_label").style="display:none;" document.getElementById("year_filter_place").innerHTML="" } } function update_pagination() { search_meta_place=document.getElementById('search_meta_data') num_pages=search_meta_place.dataset.num_pages; active_pgn=parseInt(search_meta_place.dataset.page); document.getElementById("pgn-ul").innerHTML=""; pgn_html=""; for (i = 1; i <= num_pages; i++){ if (i===active_pgn){ actv="active" }else {actv=""} pgn_li="
  • " +i+ "
  • "; pgn_html+=pgn_li; } document.getElementById("pgn-ul").innerHTML=pgn_html var pgn_links = document.querySelectorAll('.mypgn'); pgn_links.forEach(function(pgn_link) { pgn_link.addEventListener('click', paginate) }) } function post_and_fetch(data,url) { showLoading() xhr = new XMLHttpRequest(); xhr.open('POST', url, true); xhr.setRequestHeader('Content-Type', 'application/json; charset=UTF-8'); xhr.onreadystatechange = function() { if (xhr.readyState === 4 && xhr.status === 200) { var resp = xhr.responseText; resp_json=JSON.parse(resp) resp_place = document.getElementById("search_result_div") resp_place.innerHTML = resp_json['results'] search_meta = resp_json['meta'] update_search_meta(search_meta) update_pagination() hideLoading() } }; xhr.send(JSON.stringify(data)); } function unfilter() { url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":"unfilter", "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } function deactivate_all_bars(){ var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(bar) { bar.dataset.active = false bar.style = "stroke:#71a3c5;" }) } year_chart.on("created", function() { var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(check) { check.addEventListener('click', checkIndex); }) }); function checkIndex(event) { var yrchart = document.querySelectorAll('.ct-bar'); var year_bar = event.target if (year_bar.dataset.active == "true") { unfilter_res = unfilter() year_bar.dataset.active = false year_bar.style = "stroke:#1d2b3699;" } else { deactivate_all_bars() year_bar.dataset.active = true year_bar.style = "stroke:#e56f6f;" filter_year = chart_data['labels'][Array.from(yrchart).indexOf(year_bar)] url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":filter_year, "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } } function showLoading() { document.getElementById("loading").style.display = "block"; setTimeout(hideLoading, 10000); // 10 seconds } function hideLoading() { document.getElementById("loading").style.display = "none"; } -->