The objective of the present study was to determine composition in mineral elements, antisickling activity and osmotic brittleness test, twenty three extracts two plants Cyttaranthus congolensis, Hypoxis angustifolia used management sickle cell disease by traditional healers Kwilu province. Mineral analyses these were performed using X-ray fluorescence spectrometric method. Twenty three( 23) el...

BACKGROUND This study evaluated the antibacterial activity of some plants used in folklore medicine to treat diarrhoea in the Eastern Cape Province, South Africa. METHODS The acetone extracts of Acacia mearnsii De Wild., Aloe arborescens Mill., A. striata Haw., Cyathula uncinulata (Schrad.) Schinz, Eucomis autumnalis (Mill.) Chitt., E. comosa (Houtt.) Wehrh., Hermbstaedtia odorata (Burch. ex ...

Mimusops caffra E. Mey. ex A.DC and Mimusops obtusifolia Lam (both members of the Sapotaceae family), and Hypoxis colchicifolia Bak (family Hypoxidaceae) are used by traditional healers in Zululand to manage malaria. Anti-plasmodial investigation of the crude extracts and some triterpenes isolated from the plants showed activity against a chloroquine sensitive (CQS) strain of Plasmodium falcipa...

OBJECTIVE To assess the toxicity of hypoxoside taken orally by 24 patients with lung cancer. DESIGN Open study with patients taking 1,200-3,200 mg standardised Hypoxis plant extract (200 mg capsules) per day divided in 3 doses in order to maintain metabolite blood levels near 100 micrograms/ml. PARTICIPANTS AND SETTING Patients with histologically proven squamous, large-cell or adenocarcino...

OBJECTIVE To study the pharmacokinetic behaviour of hypoxoside taken orally by 24 patients with lung cancer. DESIGN Randomised open study with three single doses of 1,600, 2,400 and 3,200 mg standardised Hypoxis plant extract (200 mg capsules) and a multiple-dose study on the first 6 patients taking 4 capsules 3 times daily for 11 days. PARTICIPANTS AND SETTING Patients with histologically ...

In Africa, herbal medicines are often used as primary treatment for HIV/AIDS and for HIV-related problems. In general, traditional medicines are not well researched, and are poorly regulated. We review the evidence and safety concerns related to the use of two specific African herbals, which are currently recommended by the Ministry of Health in South Africa and member states for use in HIV: Af...