Sacha inchi meal (SIM) is the residue from processing of oil crop sacha inchi. In present study, biological enzymolysis was performed on SIM protein to obtain hydrolysates, and then antioxidant hypoglycemic activities were evaluated. The results showed that scavenging rates alkaline protease hydrolysate (SAl) protamex (SPr) ABTS free radicals close vitamin C at 5 mg/mL, amounting 99.83 ± 0.33% ...

The solid dosage forms of Gymnemic acid nanoparticulate formulations developed earlier were tested for anti-diabetic activity and hypoglycemic activity. Glucose, insulin and various biochemical parameters were monitored from blood samples of rats to study the efficacy of these formulations. The nanoformulations exhibited significant anti-hyperglycemic activity and produced substantial hypoglyce...

Background and objectives: Amongst the serious metabolic disorders, diabetes mellitus (DM) is a common disease throughout the world. The excess of morbidity and mortality associated with DM and its complications emphasize the importance of new or alternative therapeutic strategies in prevention and treatment of this chronic disorder. Medicinal herbs grow vastly in Iran and are ...

Introduction. Catharanthus roseus (L.) is used in some countries to treat diabetes. The aim of this study was to evaluate the hypoglycemic activity of extracts from the flower, leaf, stem, and root in normal and alloxan-induced diabetic mice. Methods. Roots, leaves, flowers, and stems were separated to obtain organic and aqueous extracts. The blood glucose lowering activity of these extracts wa...

Hypoglycemia is a well-recognized side effect of glucoselowering therapies in patients with diabetes mellitus. The incidence of mild self-reported hypoglycemic episodes in patients with type 1 diabetes mellitus is approximately 30 episodes per patient per year, whereas the incidence of severe hypoglycemic episodes (ie, those that require third-party assistance) may be as high as 3.2 episodes pe...

The present study was performed to determine the optimal dose of alloxan monohydrate required to induce diabetes in male BALB/c mice and investigatein vivo hypoglycemic activity of aqueous and ethylacetate leaf and stem bark extracts of Pappea capensisLin alloxanized diabetic BALB/c mice.In addition, the proximate composition of P. capensis powder was investigated. The seven groups used in dete...