We report a 36-year-old woman with primary hypothyroidism revealed by postpartum amenorrhoea-galactorrhoea associated with hyperprolactinaemia and suprasellar pituitary enlargement on magnetic resonance imaging (MRI). On thyroid hormone replacement therapy all clinical, biochemical, radiological and endocrine abnormalities disappeared. Hyperplasia of pituitary thyrotrophs and/or lactotrophs see...

Hyperprolactinaemia is an important but neglected adverse effect of antipsychotic medication [1]. It occurs frequently with conventional antipsychotics and some atypical antipsychotics (risperidone and amisulpride). We found hyperprolactinaemia in all 10 patients evaluated during therapy with low doses (50 mg per day) of amisulpride used as an augmentation to antidepressant treatment, benzodiaz...

OBJECTIVE Hyperprolactinaemia in humans may be associated with a high prevalence of obesity but the nature of this link is poorly defined. The aim of this study was to establish the relationship between hyperprolactinaemia and body weight in patients with prolactin-secreting pituitary tumours. DESIGN We conducted a retrospective study of prolactinoma patients treated at the Endocrine Institut...

Vitex agnus-castus L. (chaste tree; chasteberry) is a popular herbal treatment, predominantly used for a range of female reproductive conditions in Anglo-American and European practice. The objective of this systematic review was to evaluate the evidence for the efficacy and safety of Vitex extracts from randomised, controlled trials investigating women's health.Eight databases were searched us...

Sixteen patients with the primary empty sella syndrome were analyzed in regard to clinicalEndings. x-ray features and dynamic endocrine testing. One patient had no endocrine disturbance. three had a panhypopituitarism and one had diabetes insipidus. Hyperprolactinaemia. the most common endocrine disturbance detected was found in six patients. Other patients had some degree of partial pituitary ...