INTRODUCTION Previous studies have reported high levels of success with intraseptal injection for various dental procedures but provide limited information on the use of the injection during endodontic treatment. Therefore, the purpose of this prospective study was to determine the anesthetic efficacy of the supplemental intraseptal technique in mandibular posterior teeth diagnosed with symptom...

Inferior alveolar nerve block has a high failure rate in the treatment of mandibular posterior teeth with irreversible pulpitis. The aim of this study was to compare the anesthetic efficacy of 4% articaine, 2% lidocaine and 2% mepivacaine, all in combination with 1:100,000 epinephrine, in patients with irreversible pulpitis of permanent mandibular molars during a pulpectomy procedure. Sixty-six...

Matrix metalloproteinases (MMPs) form an enzyme family capable of degrading almost all extracellular matrix (ECM) and basement membrane (BM) components. They play an important role in normal tissue remodelling and growth, as well as in many destructive pathological conditions such as inflammation, tumour growth and metastasis. The role of MMPs in the breakdown of pulp tissue of teeth with pulpi...

INTRODUCTION The purpose of this retrospective study was to determine the anesthetic success of the inferior alveolar nerve (IAN) block, and supplemental articaine buccal infiltration after a failed IAN block, in first and second molars and premolars in patients presenting with symptomatic irreversible pulpitis. METHODS As part of 6 studies, 375 emergency patients presenting with symptomatic ...

Aim. (1) The aim of the clinical study revolves around the accurate diagnosis, proper case selection, and the management of acute irreversible pulpitis in permanent molars with closed apices using conservative and economical treatment modalities like vital pulpotomies with regenerative approaches over conventional root canal procedures. (2) To evaluate the use of autologous substances such as p...

background: endometrial cancer is the most common gynecologic malignancy that has often proceeded by a premalignant phase. modern molecular and immune staining methods for precancerous lesions diagnosis have been expanded. one of the genetic alternations in the endometrial cancer carcinogenesis is the mutational activation of the k-ras oncogene. k-ras mutation has recognized to occur at an earl...

the presence of immune factors in inflamed dental pulps, suggests that immune responses could participate in disease process. with regard to the presence of significant number of mast cells in pulpitis cases, the purpose of this study was to determine the correlation between concentration and presence of ige in supernatant fluids of explants cultures of different states of dental pulps. for thi...

Gastric hyperplastic polyps are generally considered benign lesions, although rare cases of adenocarcinoma have been reported. Two cases of intramucosal adenocarcinoma originating from gastric hyperplastic polyps that were successfully removed by endoscopic mucosal resection or endoscopic submucosal dissection are reported. On pathological examination, adenocarcinoma limited to the hyperplastic...

evaluation of enlarged follicles with unerupted teeth is always important because some changes may occur. one of the extremely rare conditions seen in dental follicles is multiple calcifying hyperplastic dental follicle. we report a case of multiple calcifying hyperplastic dental follicle. radiographs showed that mandibular third molars had a pericoronal radiolucent zone delineated by a well-de...

The ultrastructure of ethionine-induced hyperplastic liver nodules was compared to the adjacent nonnodular liver in the same rat and also to hyperplastic liver nodules induced by 2-fluorenylacetamide. Several reproducible cytostructural alterations were noted in ethionine-induced hyperplastic liver nodules of fasted animals but not in adjacent nonnodular liver. This set of alterations was quite...