We read with concern the article on passive hyperimmune therapy in the treatment of acquired immunodeficiency syndrome (AIDS).’ In this report, the investigators attempted to show the efficacy of plasma taken from asymptomatic human immunodeficiency virus (H1V)-positive donors with antibody to HIV on the clinical course of AIDS patients. The investigators set up four requirements to establish e...

The Ixodes holocyclus tick causes paralysis in up to 10,000 companion and domestic animals each year in Australia. Treatment requires the removal of the parasite and the administration of a commercial tick antiserum that is prepared from hyperimmune dogs. Each batch of this serum is initially tested for toxin-neutralising potency in a mouse bioassay that is expensive, time consuming, and subjec...

AIMS To develop an effective diagnostic kit, based on a competitive ELISA-based system (cELISA), for detecting serum antibody against peste des petits ruminants virus (PPRV). METHODS Epitope peptides of the nucleocapsid (N) protein of Tibetan PPRV were synthesized chemically and injected into rabbits to prepare hyperimmune antisera. Test sera were incubated simultaneously with hyperimmune ant...

We investigate issues surrounding an old question of Yates’ as to the existence of a minimal degree with no strong minimal cover, specifically with respect to the hyperimmune-free degrees.

We give natural examples of factors of the Muchnik lattice which capture intuitionistic propositional logic (IPC), arising from the concepts of lowness, 1-genericity, hyperimmune-freeness and computable traceability. This provides a purely computational semantics for IPC.

Soluble antigens from Besnoitia besnoiti cell culture-grown endozoites, obtained either by hypotonic lysis or by freeze-thawing and ultrasonication (FTS) of the organisms, were detected by the agar gel immunodiffusion method. Each antigenic preparation yielded 1-4 precipitin lines when reacted with the corresponding rabbit hyperimmune serum, while no reaction was observed with Besnoitia-positiv...

The purpose of this study was to determine if colostrum-deprived foals with experimentally induced Rhodococcus equi pneumonia have a decreased severity of the disease and decreased mortality rate when given hyperimmune (HI) R. equi antibody plasma (R. equi titer at least 100 % and virulence-associated protein A [VapA] at least 10000) prophylactically versus when given normal equine plasma (R. e...