We present a report of an autosomal-dominant hyper-IgE syndrome patient with vertebral aspergillosis. Early diagnosis and antifungal therapy with surgery are crucial for improving the outcome of this aggressive condition.

Hyper-IgE Syndrome (HIES), also known as Job Syndrome; is a rare genetic disorder that affects the immune system and can lead to various health complications. The text mentions cornerstone of HIES therapy proper skin care, infection prevention, aggressive treatment. Treatments for include antibiotics target S. aureus, typically used reduce incidence pneumonia risk lung damage. Skincare routines...