نتایج جستجو برای: huperzine a

تعداد نتایج: 13431799  

2013
Debin Huang Zehua Hu Zhaofen Yu

Eleutheroside B or E, the main component of Acanthopanax, can relieve fatigue, enhance memory, and improve human cognition. Numerous studies have confirmed that high doses of acetylcholine significantly attenuate clinical symptoms and delay the progression of Alzheimer's disease. The present study replicated a rat model of aging induced by injecting quinolinic acid into the hippocampal CA1 regi...

Journal: :Bioscience, Biotechnology, and Biochemistry 2016

Journal: :Current topics in medicinal chemistry 2007
H Haviv D M Wong I Silman J L Sussman

The naturally occurring alkaloid Huperzine A (HupA) is an acetylcholinesterase (AChE) inhibitor that has been used for centuries as a Chinese folk medicine in the context of its source plant Huperzia Serrata. The potency and relative safety of HupA rendered it a promising drug for the ameliorative treatment of Alzheimer's disease (AD) vis-à-vis the "cholinergic hypothesis" that attributes the c...

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