On-skin electronics, which offers an interface for extracting electrophysiological signals from skin, is intensively investigated using electrodes mounted on flexible substrates. Despite numerous efforts toward substrate design to optimize user comfort, substrates with skin-adhesion, skin-breathability, skin-compatibility, mechanical endurance, sterilizability, sustainability, and biodegradabil...

the genus malasezia currently includes fourteen species that have been isolated from healthy and diseased human and animal skin. however, there were differences with respect to the species most commonly isolated, not only in patients with various skin diseases but also between healthy individuals. the aim of this study was to analyze the prevalence of malassezia species from clinically normal s...

Skin is a valuable model organ system for better understanding the aging processes and related diseases in order to develop preventive therapeutic strategies. To study molecular mechanisms of skin associated diseases, researchers often usein vivo ex vivohuman skin, animal models, or cell culture systems. We present here novel long-term 3D that can be used process skin. Using primary dermal fibr...

Topica! tyrosine has been proposed as a tanning accelerator because tyrosine is a precursor of melanin. We tested formulations containing O, 1, and 2% L-tyrosine topically on 14 individuals daily for 28 days. Percutaneous absorption using "C tyrosine was 1.23% in 24 hr. No enhanced pigmentation was clinically evident in any of the subjects. In this study, we were unable to demonstrate that topi...

In recent years there has been increasing appreciation of the metabolic activities that occur in the skin. The concept that the skin may manufacture the complex substances necessary to perform its function is gaining increasing support. In the category of lipids it seems possible that the skin itself synthesizes from other substances the fats necessary for the epidermal "barrier," the protectiv...

Skin autografting was first described by Reverdin in 1871 [1]. The clinical utility of allograft skin as a method for wound coverage followed shortly thereafter [2]. Girdner [3] was the first to report the use of allogeneic skin to cover a burn wound; however, it wasn’t until 5 years later that Thiersch [4] described the histologic anatomy of skin engraftment and later popularized the clinical ...