نتایج جستجو برای: human ineterferon gamma

تعداد نتایج: 1739653  

Journal: :Biochemical Society transactions 2002
L G Presta R L Shields A K Namenuk K Hong Y G Meng

The binding sites on human IgG1 for human Fc gamma receptor (Fc gamma R) I, Fc gamma RIIa, Fc gamma RIIb, Fc gamma RIIIa and neonatal FcR have been mapped. A common set of IgG1 residues is involved in binding to all Fc gamma Rs, while Fc gamma RII and Fc gamma RIII utilize distinct sites outside this common set. In addition to residues which abrogated binding to the Fc gamma R, several position...

Journal: :Annals of the rheumatic diseases 1992
N J Goulding S M Knight J L Godolphin P M Guyre

The therapeutic potential of interferon gamma (IFN gamma) in a number of disease states is still being explored, but progress is hampered by the lack of a suitable measure of in vivo biological activity. To assess the in vivo biological effects of recombinant human IFN gamma (rhIFN gamma), 14 patients were studied in a randomised, prospective, double blind, placebo controlled trial of this cyto...

A. Cebulska-Wasilewska, J.K. Kim, M. Nili, T.W. Park,

Background: Boron and gadolinium are among the nuclides that hold a unique property of being a neutron capture therapy agent. Neutron beams have often a considerable portion of gamma rays with fast neutrons. Gamma rays, as beam contaminants, can cause considerable damage to normal tissues even if such tissues do contain high boron concentrations. Materials and Methods: The modification of radio...

Journal: :The Journal of biological chemistry 1998
C H Halsted E H Ling R Luthi-Carter J A Villanueva J M Gardner J T Coyle

Jejunal folylpoly-gamma-glutamate carboxypeptidase hydrolyzes dietary folates prior to their intestinal absorption. The complete folylpoly-gamma-glutamate carboxypeptidase cDNA was isolated from a pig jejunal cDNA library using an amplified homologous probe incorporating primer sequences from prostate-specific membrane antigen, a protein capable of folate hydrolysis. The cDNA encodes a 751-amin...

Journal: :Blood 1985
W Piacibello L Lu M Wachter B Rubin H E Broxmeyer

Human gamma interferon (HuIFN gamma) was assessed for its capacity to enhance release of granulocyte-macrophage colony stimulating factors (GM-CSF) from human peripheral blood monocytes. Natural HuIFN gamma (2 X 10(7) NIH reference units per milligram) at concentrations as low as 0.01 U/mL to 10 U/mL reproducibly enhanced release of GM-CSF. This enhancement was detected when T lymphocytes were ...

Background and purpose:  Background radiation exists naturally in the environment and human has been always exposed to it. These rays can affect living creatures and cause chromosomal damage, and genetic and somatic diseases. Hot water springs are a major source of background radiation. This study aimed at investigating the absorbed dose of environmental gamma and determining the annual effecti...

Journal: :PPAR Research 2008
Guido Eibl

In recent years, the study of the peroxisome proliferators activated receptor gamma (PPAR-gamma) as a potential target for cancer prevention and therapy has gained a strong interest. However, the overall biological significance of PPAR-gamma in cancer development and progression is still controversial. While many reports documented antiproliferative effects in human cancer cell and animal model...

پایان نامه :دانشگاه تربیت معلم - تهران - دانشکده ادبیات و علوم انسانی 1389

شهرهایی که در دامنه های کوهستانی شکل گرفته اند به شدت تحت تاثیر محیط فعال پیرامون خود قرار گرفته و به وسیله مخاطرات ژیومورفولوژیکی موجود در آن مورد تهدید قرار می گیرند. شهر جوانرود به دلیل قرارگیری در پاپکوهای زاگرس چین خورده و نیز به دلیل گذر روخانه فصلی و دایمی سوریر در شرق و لیله در جنوب شهر دارای مخاطرات محیطی مختلف از جمله حرکات دامنه ای و سیل و طغیان رودخانه می باشد. در تحقق حاضر به منظور...

2013
ABRAHAM SAIFER MICHAEL C. ZYMARIS HENRY BERGER

The main purpose in performing the detailed experimental studies in Part I is the application of the photometric method to the determination of the gamma globulin content of human sera. These experimental studies show that protein fractions such as albumin or alpha globulins, whose electrophoretic mobilities are far removed from gamma globulin, cause little interference with its determination. ...

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