نتایج جستجو برای: human igg

تعداد نتایج: 1668481  

Journal: :Journal of bacteriology 1995
B Serhir D Dubreuil R Higgins M Jacques

We previously reported that group D streptococci exhibited immunoglobulin G (IgG)-binding activity and that a 52-kDa IgG-binding protein was present in all Streptococcus suis strains examined (B. Serhir, R. Higgins, B. Foiry, and M. Jacques, J. Gen. Microbiol. 139:2953-2958, 1993). The objective of the present study was to purify and characterize this protein. Pig IgG were immobilized through t...

Mir Kamran Mousavi Hosseini, Mohammad Ali Jalili, Mojgan Pourmokhtar, Saleh Nasiri,

Background: In this study we have prepared the IgA solution from normal human plasma using plasma fractionation and ion exchange chromatography. Materials and Methods: Using fractionation of plasma with cold ethanol (starting with 8% ethanol), fraction III was prepared as a suitable source for IgA preparation. Then it was treated with caprylic acid for separation of impurities. For enrichm...

Journal: :The Journal of biological chemistry 1994
K Ando K Kikugawa M Beppu

When young and senescent erythrocytes, separated from freshly collected human blood, were incubated with 125I-goat anti-human IgG, binding of the IgG to the senescent cells was three times as high as that to the young cells. The release of the radioactivity from the anti-human IgG-bound senescent cells was enhanced by incubation with band 3 oligosaccharides but not by those digested with endo-b...

Journal: :The protein journal 2012
Zhengjian Lv Jianhua Wang Guoping Chen

Interactions between antibody and antigen molecules play essential roles in biological recognition processes as well as medical diagnosis. Therefore, an understanding of the underlying mechanism of antibody-antigen interactions at the single molecular level would be beneficial. In the present study, human immunoglobulin (IgG) tethered cantilevers and rat anti-human IgG functionalized gold surfa...

Journal: :Clinical chemistry 1987
R G Hamilton

Complement activation, cell surface-receptor binding, blocking activity, and possibly placental transfer are among the biologically important functional differences that have been detected between the four human IgG subclasses by use of polyclonal antisera. In 1985, a IUIS/WHO panel of immunologists, using eight immunological methods, documented the specificity of select monoclonal antibodies f...

Multiple Sclerosis (MS) is a chronic neurological disease of the central nervous system (CNS), characterised by a cellular immune response in early stages and demyelination of the CNS later. Although the cause of MS is unknown, there is much evidence that points to MS as an autoimmune disease. To test the hypotheses that an Autoantigen is involved in MS, we screened a ?gt11 human foetal spinal ...

Bruce Mazer, Majid Tebianian, Tahereh Mousavi,

The link between IL-13 and bronchial hyper-responsiveness has brought this cytokine as a potential therapeutic target for asthma and allergic diseases. At the present study, we address the role of B cell derived IL-13 in the IgE and other immunoglobulin development. Antisense oligo for human IL-13 m-RNA was used to study IgE down regulation. Human B-lymphocytes were purified by positive selecti...

2003
WAYNE E. MAGEE

Methods for preparing bentonite-gamma globulin complexes and for determining their attachment to cells in tissue culture were investigated by use of human immunoglobulin G (IgG) labeled with 125I. For virus-inhibition studies, bentonite-IgG complexes were prepared by use of human IgG with high specific neutralizing activity against coxsackievirus A21. Much of the antibody in the complex remaine...

Journal: :Journal of virology 1974
K Nordström A Forsgren P Cox

Normal human and rabbit sera when incubated with Staphylococcus aureus inhibit the adsorption of bacteriophages. The bacteriophage adsorption was also inhibited by separated normal immunoglobulin M (IgM), F(ab')(2), and Fab-fragments of IgG. No inhibition was obtained with myeloma IgG or Fc-fragments of normal human and rabbit IgG. The results indicate that the serum inhibition of bacteriophage...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2011
Zili Li Senthilkumar Palaniyandi Rongyu Zeng Wenbin Tuo Derry C Roopenian Xiaoping Zhu

IgG is a major Ig subclass in mucosal secretions of the human female genital tract, where it predominates over the IgA isotype. Despite the abundance of IgG, surprisingly little is known about where and how IgG enters the lumen of the genital tract and the exact role local IgG plays in preventing sexually transmitted diseases. We demonstrate here that the neonatal Fc receptor, FcRn, is expresse...

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