(1) Background: Interest in the application of metabolomics toward clinical diagnostics development and population health monitoring has grown significantly in recent years. In spite of several advances in analytical and computational tools, obtaining a sufficient number of samples from patients remains an obstacle. The dried blood spot (DBS) and dried urine strip (DUS) methodologies are a mini...

BACKGROUND Human peripheral blood is a promising material for biomedical research. However, various kinds of biological and technological factors result in a large degree of variation in blood gene expression profiles. METHODOLOGY/PRINCIPAL FINDINGS Human peripheral blood samples were drawn from healthy volunteers and analysed using the Human Genome U133Plus2 Microarray. We applied a novel ap...

Introduction: Boron possesses widespread properties and is important for human and animal nutrition. Since Boron is rapidly bioavailable, the objective of the present study was to determine whether acute (hourly or daily), and weekly supplementationcould have any significant biological effects on the synthesis of steroids as well as inflammatory biomarkers. Methods: Eight male volunteers part...

Background: There is an important evidence that prolonged exposure to several endocrine disrupting chemicals (EDCs). These are persistent materials with unique environmental properties such as intake of contaminated food, water and air, irrespective of proximity to industries, which are suspected to have endocrine disrupting activities. Perflurooctanoic acid (PFOA) and diethylstilbestrol (EDCs)...

BACKGROUND Results of arterial blood gas analysis can be biased by pre-analytical factors, such as time interval before analysis, temperature during storage and syringe type. OBJECTIVES To investigate the effects of samples storage temperature and time delay on blood gases, bicarbonate and PH results in human arterial blood samples. PATIENTS AND METHODS 2.5 mL arterial blood samples were dr...

Introduction Cold plasma is a self-sterilized, painless, and non-contact method in surgeries. These properties allow it to be applied to the living tissues and heat-sensitive parts. The aim of this study was to design a new cold plasma producer device and evaluate the effects of cold argon plasma on decreasing the coagulation time of blood drop in vitro and that of the injured liver blood in vi...

BACKGROUND The practice of on-ice storage of arterial-blood samples in plastic syringes for delayed analysis continues, and the effects of storage time and temperature on the measurement of blood-oxygen-saturation values (S(aO2)) have not been adequately described. OBJECTIVE To determine the effects of syringe material, storage time, and storage temperature on normal arterialized blood gas an...